Results 81 to 90 of about 208,234 (267)
CFD Analysis and Optimum Design for a Centrifugal Pump Using an Effectively Artificial Intelligent Algorithm. [PDF]
Micromachines (Basel), 2022 Wang CN, Yang FC, Nguyen VTT, Vo NTM.
europepmc +1 more source
Optimum Designs for Polynomial Extrapolation
The Annals of Mathematical Statistics, 1965 A solution is given to the problem of where to choose $k + 1$ points and what weights to assign them in order to obtain the minimum variance of what may be called an interior extrapolated value of a polynomial of degree $k$. It is assumed that observations can be taken in the interval $\lbrack -1, 1\rbrack$, except for a subinterval $(\alpha, \beta ...
openaire +3 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
OptDesign: Identifying Optimum Design Strategies in Strain Engineering for Biochemical Production. [PDF]
ACS Synth Biol, 2022 Jiang S +5 more
europepmc +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Optimum Design of a Composite Optical Receiver by Taguchi and Fuzzy Logic Methods. [PDF]
Micromachines (Basel), 2021 Wang N, Peng X, Kong L.
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Tapped-inductor bi-directional Cuk converter with high step-up/down conversion ratio and its optimum design. [PDF]
Sci Rep, 2022 Chen H, Lin WM, Liu WR, He W.
europepmc +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Mechanical Engineering JournalThis paper presents a case study of the design, fabrication, and evaluation of an automotive rear-frame model made of variable axial composites (VAC), using a tailored fiber placement (TFP) technique.
Yoshihiro IWANO +8 more
doaj +1 more source