Results 81 to 90 of about 202,035 (266)
CFD Analysis and Optimum Design for a Centrifugal Pump Using an Effectively Artificial Intelligent Algorithm. [PDF]
Micromachines (Basel), 2022 Wang CN, Yang FC, Nguyen VTT, Vo NTM.
europepmc +1 more source
Optimum Designs for Polynomial Extrapolation
The Annals of Mathematical Statistics, 1965 A solution is given to the problem of where to choose $k + 1$ points and what weights to assign them in order to obtain the minimum variance of what may be called an interior extrapolated value of a polynomial of degree $k$. It is assumed that observations can be taken in the interval $\lbrack -1, 1\rbrack$, except for a subinterval $(\alpha, \beta ...
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
OptDesign: Identifying Optimum Design Strategies in Strain Engineering for Biochemical Production. [PDF]
ACS Synth Biol, 2022 Jiang S +5 more
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Optimum Design of a Composite Optical Receiver by Taguchi and Fuzzy Logic Methods. [PDF]
Micromachines (Basel), 2021 Wang N, Peng X, Kong L.
europepmc +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Tapped-inductor bi-directional Cuk converter with high step-up/down conversion ratio and its optimum design. [PDF]
Sci Rep, 2022 Chen H, Lin WM, Liu WR, He W.
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The Annals of Mathematical Statistics, 1959 Suppose we are given $N$ objects to be weighed in $N$ weighings with a chemical balance having no bias. Let $x_{ij} = 1$ if the $j$th object is placed in the left pan in the $i$th weighing, $= -1$ if the $j$th object is placed in the right pan in the $i$th weighing, $= 0$ if the $j$th object is not weighed in the $i$th weighing. The $N$th order matrix $
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source