Results 101 to 110 of about 30,757 (251)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Electrodermal stimulation variant analysis for optimum perception in somatosensory feedback protocols

open access: yesResearch on Biomedical Engineering, 2022
Ana Clara Pereira Resende da Costa   +4 more
openaire   +1 more source

ANALYSIS OF STANDARD TRANSFORMER OIL AND VARIANT VEGETABLE OIL FOR OPTIMUM OPERATION OF TRANSFORMER

open access: yes
Abstract: The requirement to create a safer, non-flammable, and ecologically friendly transformer coolant to replace the petroleum-based oil currently used as transformer oil is the aim of this study. To identify a viable and sustainable vegetable oil substitute for transformer oil, electrical and chemical experiments were conducted on samples of melon,
Uzoma Osuji   +3 more
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Design and Control of Nonlinear Mechanical Systems for Minimum Time

open access: yesShock and Vibration, 2008
This paper presents an integrated methodology for optimal design and control of nonlinear flexible mechanical systems, including minimum time problems. This formulation is implemented in an optimum design code and it is applied to the nonlinear behavior ...
J.B. Cardoso, P.P. Moita, A.J. Valido
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A New CAM in the Market… Be Positive, Live Healthy

open access: yesPakistan Journal of Medicine and Dentistry
The later part of twentieth century has seen alternative medicine finally becoming a recognized entity, defined as a variant to conventional mode of management of diseases.
Farah Ahmed   +2 more
doaj  

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