Results 51 to 60 of about 31,983 (250)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Improved Intra-Pulse Modulation Phase Calibration Algorithm With Accelerated Entropy Minimization Optimization

IEEE Access, 2019
Intra-pulse modulation phase calibration is necessary in inverse synthetic aperture radar (ISAR) imaging of high-speed targets. Traditional intra-pulse phase error compensation strategies rarely handle the high-order and slow-time-variant phase ...
Yue Lu, Shiyou Xu, Yue Zhang, Qi Wu, Zengping Chen   +4 more
doaj   +1 more source

The variant ‘his‐box’ of the C18‐Δ9‐PUFA‐specific elongase IgASE1 from Isochrysis galbana is essential for optimum enzyme activity [PDF]

FEBS Letters, 2003
IgASE1, a C18‐Δ9‐polyunsaturated fatty acid‐specific fatty acid elongase component from Isochrysis galbana, contains a variant histidine box (his‐box) with glutamine replacing the first histidine of the conserved histidine‐rich motif present in all other known equivalent proteins. The importance of glutamine and other variant amino acid residues in the
Qi, B, Fraser, TCM, Bleakley, CL, Shaw, EM, Stobart, AK, Lazarus, CM   +5 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

THE RESULTS OF TREATMENT OF PATIENTS WITH POSTOPERATIVE VENTRAL HERNIAS

Acta Biomedica Scientifica, 2012
The article describes the experience of surgical treatment of 391 patient with postoperative ventral hernias with use of different variants of elimination of hernial defects.
V. A. Beloborodov, V. M. Tsmaylo, S. A. Kolmakov, K. P. Kuzmenko   +3 more
doaj  

Searching for the needle in the haystack: the application of a literature searching tool to retrieve information to allow optimum classification of MMR variants [PDF]

, 2020
Background: Pathogenic variants in the mismatch repair (MMR) genes are the drivers of Lynch Syndrome; optimal variant interpretation is required for the management of suspected and confirmed cases. Given the onerous nature of extracting information related to genetic variants, literature searching tools which harness artificial intelligence may aid in ...
Varun Kaushik, Finlay Macrae, John Paul Plazzer   +2 more
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Genetic Algorithm-Based Optimization of Clustering Algorithms for the Healthy Aging Dataset

Applied Sciences
Clustering is a crucial and, at the same time, challenging task in several application domains. It is important to incorporate the optimum feature finding into our clustering algorithms for better exploration of features and to draw meaningful ...
Kahkashan Kouser, Amrita Priyam, Mansi Gupta, Sanjay Kumar, Vandana Bhattacharjee   +4 more
doaj   +1 more source