Results 61 to 70 of about 13,905,601 (245)

Managing Option Fragility [PDF]

We analyze and explore option fragility, the notion that option incentives are fragile due to their non-linear payoff structure. Option incentives become weaker as options fall underwater, leading to pressures to reprice options or restore incentives ...
Brian J. Hall, Thomas A. Knox
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Option Pricing Under the Variance Gamma Process [PDF]

In this dissertation we price European and American vanilla and barrier options assuming that the underlying follows the variance gamma process. We solve numerically the problem implementing a finite difference algorithm and we present numerical ...
Fiorani, Filo
core  

Determinants of HIV infection among children born to mothers on prevention of mother to child transmission program of HIV in Addis Ababa, Ethiopia: a case control study

BMC Infectious Diseases, 2018
Background Despite wide spread use of Antiretroviral Therapy (ART) by pregnant women living with Human Immunodeficiency Virus (HIV), the transmission rate is still higher by 18% after breastfeeding ends.
Girma Alemayehu Beyene, Lelisa Sena Dadi, Solomon Berhanu Mogas   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Optimization of the vertical transmission prevention program in Guinea: impact of the improvement plan on performance indicators at large-cohort sites

AIDS Research and Therapy
Introduction Vertical transmission of HIV remains a major challenge in Guinea, especially, in low-resource rural areas. This paper presents the results of a pilot project designed to enhance the prevention of vertical transmission through a comprehensive
Soriba Camara, Tamba Mina Millimouno, Castro Gbêmêmali Hounmenou, Delphin Kolié, Kadio Jean-Jacques Olivier Kadio, Abdoulaye Sow, Sidikiba Sidibé, Alexandre Delamou   +7 more
doaj   +1 more source

Option B plus antiretroviral therapy adherence and associated factors among HIV positive pregnant women in Southern Ethiopia

BMC Pregnancy and Childbirth, 2019
Background Adherence to Option B plus Antiretroviral Therapy plays a vital role in preventing mother to child transmission of Human Immunodeficiency Virus and development of drug resistance.
Dawit Jember Tesfaye, Desalegn Tsegaw Hibistu, Teshome Abuka Abebo, Feleke Tafesse Asfaw, Kaleegziabher Lukas, Tariku Laelago, Ermias Abera Turuse, Henok Gebreyohaness Kebede, Abraham Abate Altaye, Fanuel Belayneh Bekele   +9 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The British Russian Option [PDF]

Following the economic rationale of [10] and [11] we present a new class of lookback options (by first studying the canonical 'Russian' variant) where the holder enjoys the early exercise feature of American options where upon his payoff (deliverable ...
Kristoffer Glover, Goran Peskir, Farman Samee   +2 more
core  

Exploring the acceptability of Option B plus among HIV-positive Nigerian women engaged and not engaged in the prevention of mother-to-child transmission of HIV cascade: a qualitative study

SAHARA-J, 2018
The acceptability of lifelong antiretroviral therapy (ART) among HIV-positive women in high-burden Nigeria, is not well-known. We explored readiness of users and providers of prevention of mother-to-child transmission of HIV (PMTCT) services to accept ...
Salome C. Erekaha, Llewellyn J. Cornelius, Melissa L. Bessaha, Abdulmumin Ibrahim, Gabriel D. Adeyemo, Mofoluwake Fadare, Manhattan Charurat, Echezona E. Ezeanolue, Nadia A. Sam-Agudu   +8 more
doaj   +1 more source