Results 11 to 20 of about 232,421 (202)

Mother-to-child transmission of HIV-1 and infant mortality in the first six months of life, in the era of Option B Plus combination antiretroviral therapy

International Journal of Infectious Diseases, 2021
Objectives: The aim of this study was to determine the contributions of intrauterine (IU), intrapartum (IP), and postpartum (PP) transmission to mother-to-child transmission of HIV-1 (MTCT) and infant mortality in the first 6 months of life, in the era ...
Lynn S. Zijenah, Tsitsi Bandason, Wilbert Bara, Maria Mary Chipiti, David Allan Katzenstein   +4 more
doaj   +3 more sources

Atezolizumab Monotherapy or Plus Chemotherapy in First-Line Treatment for Advanced Non-Small Cell Lung Cancer Patients: A Meta-Analysis

Frontiers in Immunology, 2021
BackgroundAtezolizumab plus chemotherapy has been recommended as a first-line treatment option for patients with advanced non-small cell lung carcinoma (NSCLC) irrespective of programmed cell death-ligand 1 (PD-L1) expression.
Dan-Ni Li, Dan-Ni Li, Dan-Ni Li, Wen-Qing Lu, Wen-Qing Lu, Wen-Qing Lu, Bo-Wen Yang, Bo-Wen Yang, Bo-Wen Yang, Ling-Yun Zhang, Ling-Yun Zhang, Ling-Yun Zhang, Bo Jin, Bo Jin, Bo Jin, Shuo Wang, Shuo Wang, Shuo Wang, Xiao-Fang Che, Xiao-Fang Che, Xiao-Fang Che, Ce Li, Ce Li, Ce Li, Yun-Peng Liu, Yun-Peng Liu, Yun-Peng Liu, Xiu-Juan Qu, Xiu-Juan Qu, Xiu-Juan Qu   +29 more
doaj   +1 more source

Cessation of breastfeeding and associated factors in the era of elimination of mother to child transmission of HIV at Ndejje health center, Uganda: a retrospective cohort study

International Breastfeeding Journal, 2020
Background Breastfeeding an infant exposed to Human Immunodeficiency Virus (HIV) carries the risk of HIV acquisition whilst not breastfeeding poses a higher risk of death from malnutrition, diarrhea, and pneumonia.
Jackslina Gaaniri Ngbapai, Jonathan Izudi, Stephen Okoboi   +2 more
doaj   +1 more source

In-vitro activity of polymyxin B, rifampicin, tigecycline alone and in combination against carbapenem-resistant Acinetobacter baumannii in Singapore. [PDF]

PLoS ONE, 2011
OBJECTIVE: Carbapenem-resistant Acinetobacter baumannii (CR-AB) is an emerging cause of nosocomial infections worldwide. Combination therapy may be the only viable option until new antibiotics become available.
Tze-Peng Lim, Thean-Yen Tan, Winnie Lee, S Sasikala, Thuan-Tong Tan, Li-Yang Hsu, Andrea L Kwa   +6 more
doaj   +1 more source

Uptake of guidelines on prevention of mother-to-child transmission of HIV in rural Tanzania: time for change

Swiss Medical Weekly, 2013
Guidelines on prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) are inconsistently implemented in low-income countries.
Anna Gamell, Emili Letang, Boniface Jullu, Geoffrey Mwaigomole, Angelo Nyamtema, Christoph Hatz, Manuel Battegay, Marcel Tanner   +7 more
doaj   +1 more source

Overcoming of Microenvironment Protection on Primary Chronic Lymphocytic Leukemia Cells after Treatment with BTK and MDM2 Pharmacological Inhibitors

Current Oncology, 2021
In B-chronic lymphocytic leukemia (B-CLL), the interaction between leukemic cells and the microenvironment promotes tumor cell survival. The Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib is one of the first-in-class molecules for the treatment of B ...
Erika Rimondi, Elisabetta Melloni, Arianna Romani, Veronica Tisato, Fabio Casciano, Gian Matteo Rigolin, Daniela Milani, Claudio Celeghini, Giorgio Zauli, Paola Secchiero, Rebecca Voltan   +10 more
doaj   +1 more source

The efficacy and safety of cadonilimab combined with lenvatinib for first-line treatment of advanced hepatocellular carcinoma (COMPASSION-08): a phase Ib/II single-arm clinical trial

Frontiers in Immunology, 2023
PurposeThis multicenter, open-label, phase Ib/II study aimed to assess the efficacy and safety of cadonilimab, a humanized, tetravalent, bispecific antibody plus lenvatinib in first-line treatment of advanced hepatocellular carcinoma (aHCC ...
Qian Qiao, Chun Han, Sisi Ye, Juan Li, Guoliang Shao, Yuxian Bai, Aibing Xu, Meili Sun, Wei Wang, Jian Wu, Ming Huang, Lijie Song, Luke Huang, Ting Liu, Wei Liu, Zhongmin Maxwell Wang, Baiyong Li, Michelle Xia, Li Bai, Li Bai   +19 more
doaj   +1 more source

Sublingual Misoprostol Versus Local Misoprostol With Foleys Catheter Cervical Insertion in Management of Missed Abortion [PDF]

Zagazig University Medical Journal
Background: Misoprostol is a successful abortion medication when administered vaginally, orally, or sublingually. we aimed for comparing safety in addition to efficacy of different regimens for missed abortion termination of through using sublingual ...
Hoda Sibai, Wael Nossair, Najma Abdelghane, Wafaa Diab   +3 more
doaj   +1 more source

Dapagliflozin plus exenatide on patients with type 2 diabetes awaiting bariatric surgery in the DEXBASU study

Scientific Reports, 2022
The glucagon-like peptide-1 receptor agonist family together with the renal sodium/glucose cotransporter-2 inhibitors have garnered interest as potential therapeutic agents for subjects with type 2 diabetes and obesity.
Carolina López-Cano, Maria Dolores Santos, Enric Sánchez, Raquel Martí, Marta Bueno, Liliana Gutiérrez-Carrasquilla, Albert Lecube   +6 more
doaj   +1 more source

Immune Checkpoint Inhibitors Plus Single-Agent Chemotherapy for Advanced Non-Small-Cell Lung Cancer After Resistance to EGFR-TKI

Frontiers in Oncology, 2021
PurposePlatinum-based chemotherapy remains the classic treatment option for patients with advanced non-small-cell lung cancer (NSCLC) who progress while receiving treatment with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs).
Haiyi Deng, Xinqing Lin, Xiaohong Xie, Yilin Yang, Liqiang Wang, Jianhui Wu, Ming Liu, Zhanhong Xie, Yinyin Qin, Chengzhi Zhou   +9 more
doaj   +1 more source