Results 191 to 200 of about 5,203,807 (351)

Encasement of the left anterior descending coronary artery: association with Takotsubo syndrome, and diagnostic and therapeutic options

, 2023
Stefan Peters
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Environmental dynamics impact whether matching is optimal. [PDF]

PNAS Nexus
Guo Y, Hermundstad AM.
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Setting the Table: Determining Which Options Clinicians Should Disclose to Patients. [PDF]

J Gen Intern Med
Dickert NW, Wendler D.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

WIC Participant and Local Agency Staff Perspectives on Increased Cash-Value Benefits for Fruits and Vegetables Within an American Indian Tribal Organization. [PDF]

Matern Child Nutr
Melnick EM, Acciai F, O'Reilly NV, Ronan AB, Jossefides M, Raval S, Dykstra T, Ohri-Vachaspati P.   +7 more
europepmc   +1 more source

Exploring optionality

Isogloss
The following paper considers the potential for optionality of anaphoric null objects in two early Romance languages: Old French and Old Tuscan. In both languages, anaphoric objects can be omitted in different syntactic contexts (e.g., in coordination with prepositional infinitives or in adjunct non-finite clauses).
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Pharmacologic Treatment of Kleine-Levin Syndrome: A Case Report and Comprehensive Review of Therapeutic Options. [PDF]

Neuropsychopharmacol Rep
Thawongit S, Siripornpanich V, Thampratankul L.   +2 more
europepmc   +1 more source