Results 121 to 130 of about 20,290 (227)

Bile acid metabolism and sleep: Mechanistic interplay and clinical implications of the gut–liver–brain axis

Sleep Research, EarlyView.
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang, Shuangyan Li, Dhirendra Paudel, Miaoqin Tan, Bin Zhang   +4 more
wiley   +1 more source

Roadmap for direct and indirect translation of optogenetics into discoveries and therapies for humans. [PDF]

Nat Neurosci
Lüscher C, Emiliani V, Farahany N, Gittis A, Gradinaru V, High KA, Roska B, Sahel JA, Yizhar O, Zeng H, Deisseroth K.   +10 more
europepmc   +1 more source

The Next Frontier: Micro/Nanorobots Operating Inside the Living Body

SmartBot, EarlyView.
Micro/nanorobots, with their tiny size and controllable motion capabilities, can perform complex and precise tasks in micro‐spaces, thus showing broad application prospects in the biomedical field. This review systematically summarizes the core advantages of micro/nanorobots in real‐time in vivo imaging, targeted drug delivery, and active barrier ...
Ningbo Yu, Jie Yang, Zicheng Ni, Yuepeng Cai, Beatriz Jurado‐Sánchez, Renfeng Dong   +5 more
wiley   +1 more source

Very-large-scale mimetic optogenetic synapses for physical reservoir computing. [PDF]

Nat Commun
Han X, Qi Z, Kundrat V, Li H, Li Z, Guo X, Mao P, Zheng W, Hou S, Liu R, Wu H, Wang P, Zak A, Liu W, Tenne R, Guo Y.   +15 more
europepmc   +1 more source

“Tone‐Arm” Neuromodulation MEMS Microcoil for In Vivo Imaging

Small, EarlyView.
ABSTRACT Implantable neural interfaces have revolutionized neuromodulation by enabling bidirectional communication between neural circuits and external devices. Yet, existing modalities face important challenges in precision, high invasiveness, and compatibility with advanced in vivo imaging systems.
Xiyuan Liu, Bingdong Chang, Kayeon Kim, Gwendoline A. E. Anand, Su Genelioglu, Changsi Cai, Anpan Han   +6 more
wiley   +1 more source

Oxytocin and Vasopressin Cross Talk Within the Brain Increases Blood Pressure. [PDF]

Circ Res
Elsaafien K, Kirchner MK, Baumer-Harrison C, Tan Y, Johnson DN, Vincent CJ, Scott KA, Zhou J, Zhang Y, Lang Y, Bulitta J, Stern JE, de Kloet AD, Krause EG.   +13 more
europepmc   +1 more source

Mass spectrometry‐based mitochondrial proteomics for cancer biomarker discovery

VIEW, EarlyView.
Figure.1 Schematic diagram of MS‐based mitochondrial proteomics for cancer biomarker discovery. The workflow highlights the integration of advanced technological platforms in mitochondrial proteomics and their application in cancer biomarker discovery.
Zheng Cao, ZiKun Song, Weijie Zhou, Xiaohui Liu, Yanling Liu, Peng R. Chen, Kun Qian   +6 more
wiley   +1 more source

Optogenetic stimulation attenuates central post-stroke pain via BDNF/TrkB signaling pathway modulation in the ascending pain modulation system. [PDF]

Sci Rep
Gu YJ, Chang J, Deng F, Deng C.
europepmc   +1 more source

Selection, counterselection, and conditional gene expression for genetic biocontrol of insects

Insect Science, EarlyView.
Selection, counterselection, and conditional expression can be used for sex separation. Selection (S) and counterselection (CS) genes are linked to the sex chromosomes (e.g., the X and Y chromosomes) to confer sex‐specific selection or counterselection based on the presence or absence of the S or CS genes.
Melanie Hempel, Zhijian Tu
wiley   +1 more source

Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead. [PDF]

Adv Genet (Hoboken)
Duan X, Zhu M, Gao S.
europepmc   +1 more source