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Optogenetics is an emerging technology for optical interrogation and control of biological function with high specificity and high spatiotemporal resolution. Mammalian cells and tissues can be sensitized to respond to light by a relatively simple and well-tolerated genetic modification using microbial opsins (light-gated ion channels and pumps).
openaire +3 more sources
Probiotic‐Based Materials as Living Therapeutics
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio +2 more
wiley +1 more source
The past, present and future of light-gated ion channels and optogenetics
The discovery of the mechanisms underlying light-gated ion channels called channelrhodospins and the subsequent development of optogenetics illustrates how breakthroughs in science and technology can span multiple levels of scientific inquiry.
Sheena A Josselyn
doaj +1 more source
A Supervised STDP-based Training Algorithm for Living Neural Networks
Neural networks have shown great potential in many applications like speech recognition, drug discovery, image classification, and object detection.
Berdichevsky, Yevgeny +6 more
core +1 more source
Hydrogels demonstrate material properties that mimic the mechanical and chemical environments of biological tissues. Yet, they face challenges during their integration into 3D interfaces. By identifying a class of thermoplastic hydrogels, a strategy is developed to pattern hydrogels in thermally drawn fibers.
Changhoon Sung +13 more
wiley +1 more source
Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics
Optogenetics allows rapid, temporally specific control of neuronal activity by targeted expression and activation of light-sensitive proteins.
Sung Il Park +27 more
semanticscholar +1 more source
Review of Multifunctional Neural Probe
Modern multifunctional neural probes for brain‐machine interfaces extend beyond basic electrical functions to incorporate chemical and optical modalities. This review explores recent advances in multifunctional probes developed for neural signal acquisition and stimulation, highlighting how these innovations enhance the precision of brain activity ...
Ziqi Jia, Yong Kyu Yoon
wiley +1 more source
Simultaneous two-photon imaging and two-photon optogenetics of cortical circuits in three dimensions
The simultaneous imaging and manipulating of neural activity could enable the functional dissection of neural circuits. Here we have combined two-photon optogenetics with simultaneous volumetric two-photon calcium imaging to measure and manipulate neural
Weijian Yang +4 more
semanticscholar +1 more source
An ingestible electronic capsule, ICOPS, enables non‐invasive optical gut stimulation in rodents. ICOPS features modular LEDs and optimized power transfer for robust, in vivo functionality. This cleanroom‐free, 3D‐printed platform offers a compact, scalable solution for optogenetically interfacing enteric neural circuits, promising advances in ...
Mohamed Elsherif +9 more
wiley +1 more source

