Results 141 to 150 of about 20,290 (227)

Synergistic Impact of Sleep Disturbance and Social Isolation in Adult but Not Adolescent Female Mice

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep quality and social isolation are two of the numerous environmental, social and health‐related factors that contribute to major depressive disorder (MDD). In human studies, a strong association has been found between sleep quality and perceived loneliness, with each potentially exacerbating the other.
Christine Egebjerg, Birgitte Rahbek Kornum   +1 more
wiley   +1 more source

Closed-loop optogenetic control of cell biology enables outcome-driven microscopy. [PDF]

Nat Commun
Passmore JB, Rates A, Schröder J, van Laarhoven MTP, Hellebrekers VJW, van Hoef HG, Geurts AJM, van Straaten W, Nijenhuis W, Berger F, Smith CS, Smal I, Kapitein LC.   +12 more
europepmc   +1 more source

Refined Division of Sleep Stages in the Mouse Based on Distributed Deep Electrodes and Underlying Infra‐Slow Oscillation

Journal of Sleep Research, EarlyView.
ABSTRACT The mouse sleep is mostly recorded with only epidural electrodes and divided simply into NREM and REM stages. With the help of distributed intracerebral triplet electrodes, we searched for possible new electrophysiological signatures to characterise more specific sleep substages within the timeframe of seconds to tens of minutes.
Nanxiang Jin, Sara Häkli, Keerthana Malathi, Hennariikka Koivisto, Theodor Boc, Jonas Schimmel, Eric Castell‐Caubet, Irina Gureviciene, Heikki Tanila   +8 more
wiley   +1 more source

When Safety Fails to Update: Altered Dopamine Prediction Signals in Extinction-Deficient Mice. [PDF]

eNeuro
Hanafy MK.
europepmc   +1 more source

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

Plant, Cell &Environment, EarlyView.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang, Fengjiao Wang, Ran Du, Tao Li, Shaoqun Zhou, Jianbin Yan, Wei Li   +6 more
wiley   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

Demonstration of the photo-controllability of the bistable opsin OPN5 using upconversion nanoparticles with multiple emission peaks upon near-infrared photoexcitation. [PDF]

Nanoscale Adv
Kotegawa F, Takahashi M, Higashimine K, Hiratsuka Y, Matsumura K, Kojima D, Maenosono S.   +6 more
europepmc   +1 more source

Update on cellular expression and function of ANO1 channels in urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley   +1 more source

Rewiring gene circuits to dissect oscillatory signaling dynamics. [PDF]

Genes Dev
van Oostrom MJ, Sonnen KF.
europepmc   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source