Results 141 to 150 of about 58,764 (371)

Cardiac optogenetics

open access: yesAmerican Journal of Physiology-Heart and Circulatory Physiology, 2013
Optogenetics is an emerging technology for optical interrogation and control of biological function with high specificity and high spatiotemporal resolution. Mammalian cells and tissues can be sensitized to respond to light by a relatively simple and well-tolerated genetic modification using microbial opsins (light-gated ion channels and pumps).
openaire   +3 more sources

Probiotic‐Based Materials as Living Therapeutics

open access: yesAdvanced Materials, EarlyView.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio   +2 more
wiley   +1 more source

The past, present and future of light-gated ion channels and optogenetics

open access: yeseLife, 2018
The discovery of the mechanisms underlying light-gated ion channels called channelrhodospins and the subsequent development of optogenetics illustrates how breakthroughs in science and technology can span multiple levels of scientific inquiry.
Sheena A Josselyn
doaj   +1 more source

A Supervised STDP-based Training Algorithm for Living Neural Networks

open access: yes, 2018
Neural networks have shown great potential in many applications like speech recognition, drug discovery, image classification, and object detection.
Berdichevsky, Yevgeny   +6 more
core   +1 more source

Optogenetic neuroregeneration

open access: yesNeural Regeneration Research, 2022
Janovjak, Harald, Kleinlogel, Sonja
openaire   +4 more sources

Thermally Drawn Multifunctional All‐Hydrogel Fibers for Anti‐Fibrotic and Multimodal Neural Interfaces

open access: yesAdvanced Materials, EarlyView.
Hydrogels demonstrate material properties that mimic the mechanical and chemical environments of biological tissues. Yet, they face challenges during their integration into 3D interfaces. By identifying a class of thermoplastic hydrogels, a strategy is developed to pattern hydrogels in thermally drawn fibers.
Changhoon Sung   +13 more
wiley   +1 more source

Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics

open access: yesNature Biotechnology, 2015
Optogenetics allows rapid, temporally specific control of neuronal activity by targeted expression and activation of light-sensitive proteins.
Sung Il Park   +27 more
semanticscholar   +1 more source

Review of Multifunctional Neural Probe

open access: yesAdvanced Materials Interfaces, EarlyView.
Modern multifunctional neural probes for brain‐machine interfaces extend beyond basic electrical functions to incorporate chemical and optical modalities. This review explores recent advances in multifunctional probes developed for neural signal acquisition and stimulation, highlighting how these innovations enhance the precision of brain activity ...
Ziqi Jia, Yong Kyu Yoon
wiley   +1 more source

Simultaneous two-photon imaging and two-photon optogenetics of cortical circuits in three dimensions

open access: yeseLife, 2018
The simultaneous imaging and manipulating of neural activity could enable the functional dissection of neural circuits. Here we have combined two-photon optogenetics with simultaneous volumetric two-photon calcium imaging to measure and manipulate neural
Weijian Yang   +4 more
semanticscholar   +1 more source

Wirelessly Powered Ingestible Capsule for Optical Stimulation of the Gastrointestinal Tract in Rodents

open access: yesAdvanced Materials Technologies, EarlyView.
An ingestible electronic capsule, ICOPS, enables non‐invasive optical gut stimulation in rodents. ICOPS features modular LEDs and optimized power transfer for robust, in vivo functionality. This cleanroom‐free, 3D‐printed platform offers a compact, scalable solution for optogenetically interfacing enteric neural circuits, promising advances in ...
Mohamed Elsherif   +9 more
wiley   +1 more source

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