Results 271 to 280 of about 55,224 (387)

Recent advances in optogenetics and pharmacogenetics [PDF]

, 2013
Gary Aston‐Jones, Karl Deisseroth
openalex   +1 more source

Optogenetic inhibition [PDF]

Nature Methods, 2020
openaire   +2 more sources

The TissueTractor: A Device for Applying Large Strains to Tissues and Cells for Simultaneous High‐Resolution Live Cell Microscopy

Small Methods, EarlyView.
Mechanical strain influences tissue development, homeostasis, and disease. The TissueTractor, a high‐strain stretcher system, enables high‐resolution imaging of live tissues and cells under strain, revealing cellular strain heterogeneity, cytoskeletal remodeling, and morphological adaptations in various model systems.
Jing Yang, Emily Hearty, Yingli Wang, Deepthi S. Vijayraghavan, Timothy Walter, Sommer Anjum, Carsten Stuckenholz, Ya‐Wen Cheng, Sahana Balasubramanian, Yicheng Dong, Adam V. Kwiatkowski, Lance A. Davidson   +11 more
wiley   +1 more source

Light-based technologies in immunotherapy: advances, mechanisms and applications. [PDF]

Immunotherapy
Frumento D, Ţălu Ș.
europepmc   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

Small Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai, Jiawen Wang, Zihuan Lin, Danni Yu, Hui Yang, Jinsong Wei, Xiaoyu Li, Hao Hu, Chao Ni, Bing Zhao   +9 more
wiley   +1 more source

Gastroesophageal Balloon Tamponade Tube Placement for Acute Variceal Hemorrhage. [PDF]

ATS Sch
Mowry CJ, McIlvain C, Kriss MS, Neumeier AT, Moreira ME.   +4 more
europepmc   +1 more source

In vivo optogenetic tracing of functional corticocortical connections between motor forelimb areas [PDF]

, 2013
Riichiro Hira, Fuki Ohkubo, Yasuhiro Tanaka, Yoshito Masamizu, George J Augustine, Haruo Kasai, M Matsuzaki   +6 more
openalex   +1 more source

Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications

Small Structures, EarlyView.
This review summarizes the fabrication methods, properties, and applications of conductive hydrogels in neural interfaces. Finally, the prevailing challenges and outlines of future directions in the field of conductive hydrogels for neural interfaces are provided, emphasizing the need for interdisciplinary research to address issues such as long‐term ...
Xin‐Yu Xue, Lu Han, He‐Qing Cai, Kou Zhang, Zhi‐Cheng Sun, Ru‐Ping Liu, Tian‐Hao Wang, Fu‐Hong Pan, Wei‐Tao Man, Dong Wang, Juan Liu   +10 more
wiley   +1 more source

Optogenetic interrogations of the neural circuits underlying addiction [PDF]

, 2013
Jonathan P. Britt, Antonello Bonci
openalex   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source