Results 281 to 290 of about 55,224 (387)

POT, an optogenetics-based endogenous protein degradation system. [PDF]

open access: yesCommun Biol
Chen Y   +7 more
europepmc   +1 more source

Microscopy and spectroscopy approaches to study GPCR structure and function

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl   +2 more
wiley   +1 more source

ESG‐1‐60 and ESG‐1‐61: Novel dopamine D3 receptor‐preferring partial agonists/antagonists that inhibit cocaine taking and seeking in rodents

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Preclinical studies suggest that highly selective dopamine D3 receptor (D3R) antagonists or partial agonists hold promise for treating substance use disorders. However, their limited effectiveness in reducing cocaine self‐administration is a major drawback.
Omar Soler‐Cedeño   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy