Results 281 to 290 of about 58,764 (371)

Biotechnical Multiscale Engineering of Scaffolds for Stem Cell and Organoid Research

open access: yesSmall, EarlyView.
Biotechnical multiscale engineering consideration of geometric and structural parameters, which is called biotechnical multiscale engineering, has an influence on stem cell development and organogenesis comparable to that of molecular genetics and biochemical parameters.
Merle‐Johanna Küstner   +13 more
wiley   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

open access: yesSmall Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai   +9 more
wiley   +1 more source

Protein design accelerates the development and application of optogenetic tools. [PDF]

open access: yesComput Struct Biotechnol J
Zhu L   +6 more
europepmc   +1 more source

Multi‐Channel Neural Interface for Neural Recording and Neuromodulation

open access: yesSmall Methods, EarlyView.
This review highlights recent advances in multi‐channel neural interface technologies, covering both high‐resolution electrophysiological recording systems and multifunctional platforms with integrated capabilities. It also discusses innovations in structure and materials for reduced invasiveness, state‐of‐the‐art data analysis, including machine ...
Eunmin Kim   +9 more
wiley   +1 more source

Closed-loop optogenetic intervention in mice

open access: green, 2013
Caren Armstrong   +3 more
openalex   +2 more sources

Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues

open access: yesSmall Methods, EarlyView.
This review summarizes recent advances in nongenetic optoelectronic technologies for the modulation of excitable biotissues, covering material selection, device design, and working principles, as well as characterization methods. Representative applications in in vitro and in vivo models of the cardiac, central, and peripheral nervous systems are ...
Qi Wang, Jinghua Li
wiley   +1 more source

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