Results 61 to 70 of about 32,941 (266)
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai +13 more
wiley +1 more source
Monica Samant,1 Rupam Mhatre,1 Rakesh Kaushal,2 Suhas Haldipurkar,1 Sabyasachi Sengupta1,3 1Laxmi Eye Hospital & Institute, Panvel, India; 2Laxmi College of Optometry, Panvel, India; 3Future Vision Eye Care, Mumbai, IndiaCorrespondence: Sabyasachi ...
Samant M +4 more
doaj
Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen +10 more
wiley +1 more source
Early Adoption and Utilization of Perfluorohexyloctane for Dry Eye Disease in the United States
Bridgitte Shen Lee,1 Lia Pizzicato,2 Elizabeth Langford,2 Liucheng Shi,2 Victoria Divino,2 Adam Alexander,3 Abhishek A Nair4 1Vision Optique, Houston, TX, USA; 2Real World Solutions, IQVIA, Falls Church, VA, USA; 3Medical Affairs, Bausch + Lomb ...
Shen Lee B +6 more
doaj
Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su +8 more
wiley +1 more source
ABSTRACT Background Patients with HPV+ oropharyngeal cancer (OPC) have worse outcomes with longer smoking history (≥ 10 pack‐years). This has been confirmed in trials of primary radiotherapy but not surgery, suggesting differential smoking impact by treatment received. We assessed smoking‐related outcomes at a single institution.
Michelle M. Kwan +17 more
wiley +1 more source
ABSTRACT Background We compared treatment delays, costs, and management impact between oropharyngeal squamous cell carcinoma (OPSCC) patients undergoing in‐office versus general anesthesia panendoscopy‐guided biopsies in two large tertiary centers in a public healthcare system. Methods All OPSCC patients included were treated between 2010 and 2024 with
Samuel Bellavance +10 more
wiley +1 more source
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange +16 more
wiley +1 more source
Eagle's Syndrome Presenting With Peripheral Facial Palsy—A Case Report
ABSTRACT Background Eagle's syndrome is a condition caused by an elongated styloid process and is characterized by various symptoms such as cervicofacial pain, foreign body sensation, headache, odynophagia, and otalgia. However, the occurrence of a unilateral peripheral facial palsy as a symptom of Eagle's syndrome has been described only rarely ...
Vincent Holtmann +3 more
wiley +1 more source

