Results 201 to 210 of about 8,117,567 (291)

Design and application of a web-based intelligent ophthalmic image analysis teaching platform. [PDF]

open access: yesFront Med (Lausanne)
Chen J   +7 more
europepmc   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale   +3 more
wiley   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2289-2308, October 2026.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu   +23 more
wiley   +1 more source

Trigonelline Alleviates Neuroinflammation in AAV‐SynA53T Parkinson's Disease Model Mice: Involvement of PI3K/AKT–NF‐κB Signaling and Gut Microbial‐Metabolic Remodeling

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
Trigonelline alleviated motor deficits, α‐synuclein‐associated pathology, and neuroinflammatory changes in AAV‐SynA53T mice. These effects were accompanied by reduced PI3K/AKT–NF‐κB signaling activity, improved intestinal barrier‐associated features, and gut microbiota–metabolome remodeling.
Mozi Chen   +10 more
wiley   +1 more source

Müller Glia–Vasculature Interactions in the Developing Retina

open access: yesGlia, Volume 74, Issue 10, October 2026.
Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Samira Monshietehadi   +6 more
wiley   +1 more source

Health System Factors in Head and Neck Cancer Diagnosis: A HEADSpAcE Consortium Qualitative Study in Glasgow and Montevideo

open access: yesHead &Neck, Volume 48, Issue 10, Page 2849-2862, October 2026.
ABSTRACT Background Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...
Grant Creaney   +196 more
wiley   +1 more source

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