Results 11 to 20 of about 390,775 (382)

Democratizing neural machine translation with OPUS-MT [PDF]

open access: yesLanguage Resources and Evaluation, 2022
This paper presents the OPUS ecosystem with a focus on the development of open machine translation models and tools, and their integration into end-user applications, development platforms and professional workflows.
J. Tiedemann   +9 more
semanticscholar   +1 more source

20‐year trajectories of positive and negative symptoms after the first psychotic episode in patients with schizophrenia spectrum disorder: results from the OPUS study

open access: yesWorld Psychiatry, 2023
This study aimed to identify the 20‐year trajectories of positive and negative symptoms after the first psychotic episode in a sample of patients with an ICD‐10 diagnosis of schizophrenia spectrum disorder, and to investigate the baseline characteristics
M. Starzer   +5 more
semanticscholar   +1 more source

Clinical Recovery and Long-Term Association of Specialized Early Intervention Services vs Treatment as Usual Among Individuals With First-Episode Schizophrenia Spectrum Disorder: 20-Year Follow-up of the OPUS Trial.

open access: yesJAMA psychiatry, 2023
Importance The OPUS 20-year follow-up is the longest follow-up of a randomized clinical trial testing early intervention services (EIS) among individuals with first-episode schizophrenia spectrum disorder.
Helene Gjervig Hansen   +5 more
semanticscholar   +1 more source

The OPUS-MT Dashboard – A Toolkit for a Systematic Evaluation of Open Machine Translation Models

open access: yesAnnual Meeting of the Association for Computational Linguistics, 2023
The OPUS-MT dashboard is a web-based platform that provides a comprehensive overview of open translation models. We focus on a systematic collection of benchmark results with verifiable translation performance and large coverage in terms of languages and
J. Tiedemann, Ona de Gibert
semanticscholar   +1 more source

Online Mendelian Inheritance in Man (OMIM®): Victor McKusick's magnum opus

open access: yesAmerican Journal of Medical Genetics. Part A, 2021
Victor McKusick's many contributions to medicine are legendary, but his magnum opus is Mendelian Inheritance in Man (MIM), his catalog of Mendelian phenotypes and their associated genes.
A. Hamosh   +4 more
semanticscholar   +1 more source

OPUS-Rota5: A Highly Accurate Protein Side-chain Modeling Method with 3D-Unet and RotaFormer

open access: yesbioRxiv, 2023
Accurate protein side-chain modeling is crucial for protein folding and design. This is particularly true for molecular docking as ligands primarily interact with side chains. A protein structure with large errors in side chains has limited usage such as
Gang Xu   +4 more
semanticscholar   +1 more source

Safety of macitentan for the treatment of pulmonary hypertension: Real‐world experience from the OPsumit® USers Registry (OPUS) and OPsumit® Historical USers cohort (OrPHeUS)

open access: yesPulmonary Circulation, 2022
Macitentan is an oral endothelin receptor antagonist for the management of pulmonary arterial hypertension (PAH). The OPsumit® USers Registry (OPUS) and the OPsumit® Historical USers cohort (OrPHeUS) medical chart review provide real‐world data for ...
V. McLaughlin   +12 more
semanticscholar   +1 more source

OPUS-DSD: deep structural disentanglement for cryo-EM single-particle analysis

open access: yesbioRxiv, 2022
Cryo-electron microscopy (cryo-EM) captures snapshots of dynamic macromolecules, collectively illustrating the involved structural landscapes. This provides an exciting opportunity to explore the structural variations of macromolecules under study ...
Zhenwei Luo   +3 more
semanticscholar   +1 more source

OPUS-Mut: Studying the Effect of Protein Mutation through Side-Chain Modeling

open access: yesbioRxiv, 2022
Predicting the effect of protein mutation is crucial in many applications such as protein design, protein evolution, and genetic disease analysis.
Gang Xu, Qinghua Wang, Jianpeng Ma
semanticscholar   +1 more source

Studying protein-protein interaction through side-chain modeling method OPUS-Mut

open access: yesbioRxiv, 2022
Protein side chains are vitally important to many biological processes such as protein-protein interaction. In this study, we evaluate the performance of our previous released side-chain modeling method OPUS-Mut, together with some other methods, on ...
Gang Xu   +3 more
semanticscholar   +1 more source

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