Results 171 to 180 of about 57,665 (244)

Phosphate‐ and pH‐dependent self‐assembly of recombinant spider silk proteins

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract The process of molecular self‐assembly is an omnipresent mechanism in nature to generate a variety of efficient and functional hierarchical architectures, and inspires tailored material design and development. Thereby, self‐assembly is based on a controlled interplay and association of monomers into highly ordered structures triggered by ...
Vanessa T. Trossmann   +5 more
wiley   +1 more source

ConforFold recovers alternative protein conformations beyond MSA subsampling

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Conformational changes underlie many aspects of protein function, yet current structure prediction tools remain limited in their ability to systematically sample structural ensembles. Here, we present ConforPSSP and ConforFold, a combined framework that integrates secondary‐structure sampling into a deep learning‐based prediction to recover ...
Raulia Syrlybaeva, Eva‐Maria Strauch
wiley   +1 more source

copick: An open dataset interface and toolkit for collaborative annotation and analysis of cryo‐electron tomography data

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Cryo‐electron tomography (cryoET) enables visualization of macromolecular complexes within intact cellular environments. Continued improvements in instrumentation, sample preparation, and data‐processing pipelines have increased both the scale and the complexity of cryoET datasets, making manual analysis challenging.
Utz Heinrich Ermel   +9 more
wiley   +1 more source

Family‐level specialization in protein domain insertion architectures

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Domain insertion creates architectures where one domain interrupts another's sequence. Analysis across 2.7 million classified domains reveals that insertions occur in 20% of multidomain proteins, with 331 families exhibiting consistent architectural roles: 162 function exclusively as hosts, while 169 exclusively serve as inserted modules, such
R. Dustin Schaeffer   +4 more
wiley   +1 more source

Substrate‐Tight Graphene Transmembrane‐nanofluidic Devices

open access: yesSmall, Volume 22, Issue 25, 4 May 2026.
This study demonstrates that the covalent coupling of a pyrene layer to a silicon nitride substrate using silane and peptide chemistry increases the adhesion of graphene to the substrate and prevents the delamination of graphene. 76.2% of the devices with free‐standing graphene are successful devices for ion transport measurement in 0.1 M HCl ...
Xiaofang Kang   +7 more
wiley   +1 more source

Brillouin Scattering Observations of Elastic Behavior Across the Post‐Stishovite Transition Under Deviatoric Stress in Polycrystalline Al‐Bearing Stishovite

open access: yesJournal of Geophysical Research: Solid Earth, Volume 131, Issue 5, May 2026.
Abstract Stishovite (SiO2), a key phase in subducted mid‐ocean ridge basalt (MORB), undergoes a ferroelastic transition to a CaCl2‐type structure, potentially explaining localized shear wave velocity (VS) anomalies in the shallow to mid‐lower mantle. However, the phase boundary determining this transition remains debated.
Ewa Krymarys   +6 more
wiley   +1 more source

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