Results 91 to 100 of about 6,988 (158)
Estudio sobre Diego Andrés Rocha (Sevilla, 1607-Lima, 1688) y su obra Tratado único y singular del origen de los indios occidentales (Lima, 1681) para contextualizar la publicación de unas «Adiciones» que sólo se incorporaron en algunos ejemplares de la
Bernat Hernández, Mary A. Wolfson
doaj +1 more source
Genes Associated With Fracture Risk in Thoroughbred Horses Have Novel Roles in Osteogenesis
ABSTRACT Bone fractures in Thoroughbred racehorses are a major welfare problem. Genetic factors contribute to fracture risk. Cell models have previously identified 112 differentially expressed genes in bone‐forming osteoblasts derived from horses at high and low genetic risk of fracture. However, 42 of these genes have no published role in bone.
Amy C. Ross +5 more
wiley +1 more source
Bard1‐mediated ubiquitination of Hnrnpa2b1 in mice with PSCI destabilizes Sptbn2, which prevents the membrane translocation of Slc7a11 and reduces cystine uptake. This disruption of antioxidant defense triggers ferroptosis in hippocampal neurons, highlighting a novel molecular pathway linking post‐stroke cognitive impairment to ferroptosis of ...
Tuming Li +6 more
wiley +1 more source
ADF downregulates TLR4, reducing hypothalamic and hepatic inflammation, with stronger effects in females. ADF enhances leptin sensitivity in aging by reducing SOCS3 and upregulating ObRb, thereby improving metabolic function. ADF reduces retroperitoneal fat and glucose levels, with females experiencing greater fat loss.
Ozgen Kilic‐Erkek +3 more
wiley +1 more source
Genetic analysis of primary lung interdigitating dendritic cell sarcomas
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov +6 more
wiley +1 more source
We developed a GalNAc‐conjugated siRNA targeting hepatic XDH, which effectively reduces uric acid production by silencing XDH expression, offering a promising therapeutic approach for hyperuricemia. ABSTRACT Hyperuricemia (HUA) is primarily driven by hepatic overproduction of urate, mediated by xanthine dehydrogenase (XDH).
Tingke Tang +12 more
wiley +1 more source
Participación de enfermería en la vigilancia y prevención de la resistencia antimicrobiana. [PDF]
Pazin-Filho A.
europepmc +1 more source
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi +15 more
wiley +1 more source
Un nuevo volumen de "Sources Chrétiennes" sobre Orígenes
Dada la predilección de la colección “Sources Chrétiennes” por Orígenes, esta nota añade notas y comentarios a un nuevo volumen: las Homilías sobre san Lucas.
José Antonio de Aldama
doaj
These findings provide strong mechanistic evidence for VOCs mediating pest resistance and suggest that exposure to herbivore‐induced, plant‐derived VOCs can enhance pest resistance in potato crops. These results might offer novel information for developing ecologically sustainable plant volatile‐based strategies for boosting protection against pests in
Lucía Martín‐Cacheda +5 more
wiley +1 more source

