Results 51 to 60 of about 5,729,296 (288)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Ricâl Tenkidinin Rivayet Pratiklerine Etkisi: Süleyman b. Erkam Özelinde Bir İnceleme

Marife Dini Araştırmalar Dergisi
Bu çalışma, muhaddislerin, zayıf râvilerden uzak durulması yönündeki eğitsel müdahalelerinin etkinliğini bir râvi üzerinden değerlendirmektedir. Araştırma kapsamında örnek olarak seçilen râvi, dönemin muhaddisleri tarafından "Biz gençken hocalarımız ...
Mustafa Oral
doaj   +1 more source

The determination of short circuits and grounding faults in electric power systems using time-frequency analysis

Journal of Energy in Southern Africa, 2017
In order to ensure that electrical energy reaches consumers uninterrupted, researchers constantly try to improve power transmission lines. To realize this improvement, probable faults should be analysed through every known method, and new methods should ...
Vedat Esen, Bulent Oral Oral, Tahir Cetin Akinci   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Ticaret Kavramı Bağlamında Kur’ân’da Uhrevî Ticaret

Antakiyat, 2021
Cahiliye dönemi toplumu, Allah ile bağlantısını bütünüyle koparmış veya Allah ile ilişkisini sorunlu hâle getirmiş, şirkin ve hurafelerin henüz yozlaştırmadığı saf/katışıksız vahyin ortamından olabildiğince uzaklaşmış, çok azı haricinde dünya hayatı ...
Murat Oral
doaj  

Multifocal Epithelial Hyperplasia, a Rare Oral Infection in the Iranian Population: A Case Report [PDF]

Journal of Research in Applied and Basic Medical Sciences, 2023
Multifocal epithelial hyperplasia (MEH) or Heck’s disease is a rare, benign, non-common, self-limiting viral infection of the oral mucosa that is caused by human papillomavirus (HPV), especially subtype 13 or 32.
Maryam Jalili Sadrabad, Shabnam Sohanian, Sanaz Asadi, Khatere Kheirollahi   +3 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

İbn Teymiyye ve "Mukaddimetun fî Usûli’t-Tefsir" Adlı Eseri

Artuklu Akademi, 2018
Hicrî VII. yüzyıl, Müslümanlar açısından çok zorlu ve karmaşık bir dönem olmuştur. Bu dönemde mezhepsel ihtilâflar artmış, ilim gizlenmiş ve Müslümanlar, Moğolların saldırılarına marûz kalmışlardır.
Murat Oral
doaj