Results 121 to 130 of about 5,189,653 (310)

Investigation of effects of two environmental heavy metals in a combined exposure model on the nervous system in rats [PDF]

open access: yes, 2012
In the present study, the interaction of inhalational and oral exposure to manganese and lead was investigated. Young adult male Wistar rats (2 x 10 per group) were treated orally with MnCl2 (15 and 60 mg/kg b.w.) or Pb acetate (80 and 320 mg/kg) for 3 ...
Horváth, Edina   +3 more
core  

Predicting Pharmacokinetics of Active Constituents in Spatholobi caulis by Using Physiologically Based Pharmacokinetic Models

open access: yesPharmaceuticals
Background/Objectives: Spatholobi Caulis (SPC) is a medicinal plant that mainly grows in China and Southeast Asian countries and commonly used in clinics; the pharmacokinetic characteristics in humans need to be determined.
Xiaoyan Liu   +7 more
doaj   +1 more source

Effect of oral genistein administration in early and late phases of allergic encephalomyelitis [PDF]

open access: yes, 2014
Objective(s): Experimental allergic encephalomyelitis (EAE) is an autoimmune disease validated as animal model of multiple sclerosis (MS). Administration of genistein, a phytoestrogenic component of soy, to mice at the onset of EAE is known to attenuate ...
Alizadeh, A.   +5 more
core   +1 more source

Lactate administration induces skeletal muscle synthesis by influencing Akt/mTOR and MuRF1 in non‐trained mice but not in trained mice

open access: yesPhysiological Reports
The perception regarding lactate has changed over the past decades, and some of its physiological roles have gradually been revealed. However, the effects of exogenous lactate on skeletal muscle synthesis remain unclear.
Sunghwan Kyun   +5 more
doaj   +1 more source

Pharmacokinetics and Ex Vivo Activity of 7-Methylxanthine, an Inhibitor of Monosodium Urate Crystallization

open access: yesBiomedicines
Background/Objectives: 7-Methylxanthine (7-MX) is a naturally occurring metabolite of caffeine and theobromine that can inhibit the crystallization of monosodium urate (MSU) and may be useful for the prevention or treatment of gout.
Miguel D. Ferrer   +6 more
doaj   +1 more source

Absorption of Free Acid, Potassium, and Benzathine Phenoxymethylpenicillin after Oral Administration [PDF]

open access: green, 1957
Jennifer M. Colquhoun   +3 more
openalex   +1 more source

PK-PD modelling of norfloxacin after oral administration in rabbits [PDF]

open access: yesVeterinary World, 2010
Norfloxacin posses a wide spectrum of activity, excellent tissue penetration and is rapidly bactericidal at low concentrations and hence an attempt was made to integrate reported pharmacodynamic data with pharmacokinetic data of norfloxacin after oral ...
B.H. Pavithra   +1 more
doaj  

Parental Perceptions of Oral Health and School-Based Dental Sealant Programs [PDF]

open access: yes, 2016
Introduction: Community Health Needs Assessment (University of Vermont Medical Center, 2013) Identified oral health in pediatric population as a primary concern Barriers to dental care cited: access, affordability, education School-Based Sealant Program (
Cole, Julie   +9 more
core   +1 more source

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