Results 161 to 170 of about 1,740,939 (308)

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

Oral administration of crocin significantly alleviated anxiety, and depressive-like behavior following ethanol and nicotine abstinence in adolescent male rats. [PDF]

Sci Rep
Kakhki S, Fadavi Razdabi E, Mohammadzadeh F, Abbaszade-Cheragheali A, Jomehpour M, Beheshti F.   +5 more
europepmc   +1 more source

Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia

Advanced Healthcare Materials, EarlyView.
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Junying Zhang, Tianyu Shao, Hailiang Li, Luying Zhu, Lamyaa Albakr, Nial J. Wheate, Lifeng Kang, Chungyong Wu   +7 more
wiley   +1 more source

Oral administration of <i>Lactiplantibacillus plantarum</i> GKK1 ameliorates atopic dermatitis in a mouse model. [PDF]

Front Microbiol
Lin TC, Wu YC, Tsai YS, Lin SW, Chen CC, Chen MJ, Chen YP.   +6 more
europepmc   +1 more source

Studies on Griseofulvin. 1. Serum Griseofulvin Levels after Oral Administration. (Studies on Antifungal Agents. VI. Report)

, 1965
Tadashi Shimazaki
openalex   +2 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

A single oral administration of resveratrol cocrystals enables potent antisepsis therapy via interfering neutrophil extracellular traps formation. [PDF]

Int J Pharm X
Wei J, Inam M, Mo H, Huang J, Zhao H, Zhong A, Tang X, Deng E, Xu C, Chen X, Mao H, Chen W, Mo J, Zhu Y.   +13 more
europepmc   +1 more source

STUDIES ON THE ORAL ADMINISTRATION OF SALIVAPAROTIN-A II. EFFECTS ON THE EPIPHYSEAL GROWTH OF TIBIA IN RATS

, 1965
Yosoji Ito, CHIAKI MORIWAKI, Hiroshi Moriya   +2 more
openalex   +2 more sources

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Pharmacokinetics and Safety of Polaprezinc Granules Oral Administration in Healthy Chinese Volunteers Under Fasting and Fed Conditions. [PDF]

Clin Transl Sci
Xiao M, Dou T, Ji J, Zhu C, Yuan Y, Zhou H, Li F, Li G, Li S.   +8 more
europepmc   +1 more source