Results 91 to 100 of about 1,458,916 (304)
Рациональная фармакотерапия в кардиологии, 2015 The clinical significance of the patient genetic characteristics in the individual pharmacological response to oral anticoagulants is considered. Possible tactics of warfarin dosing and new oral anticoagulants choice on the basis of pharmacogenetic ...
D. A. Sychev +3 more
doaj +3 more sources
, 2015 Jerome Ment Department of Cardiology, Birmingham Heartlands Hospital, Birmingham, UK Abstract: Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide.
Ment J
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British Journal of Clinical Pharmacology, EarlyView.Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Background Long‐acting intramuscular cabotegravir plus rilpivirine (LA‐CAB + RPV) is an effective maintenance antiretroviral regimen for virologically suppressed people with HIV. However, its use in individuals receiving chronic anticoagulation is limited by concerns regarding intramuscular bleeding risk, and real‐world data are scarce.
Montserrat Laguno +13 more
wiley +1 more source
Therapeutic Advances in Drug Safety, 2019 The aim of this review was to identify patient-focused interventions that have been trialed to support vulnerable patient populations taking oral anticoagulants (warfarin and the direct-acting oral anticoagulants (DOACs)) such as older persons (65 years ...
Angela Yiu, Beata Bajorek
doaj +1 more source
Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women
British Journal of Clinical Pharmacology, EarlyView.Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea +10 more
wiley +1 more source
Anticoagulant Therapy in “Fragile” Elderly Patients: Current State of the Problem
Рациональная фармакотерапия в кардиологии, 2019 The review focuses on the use of oral anticoagulants in fragile elderly patients. The issues of prevalence and diagnosis of senile asthenia syndrome or “fragility”, as well as its effects on the risks of thrombosis, bleeding and death, are discussed. The
N. M. Vorobyeva, O. N. Tkacheva
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza +12 more
wiley +1 more source
Use of direct oral anticoagulants for chronic thromboembolic pulmonary hypertension
Clinics, 2018 OBJECTIVES: Chronic thromboembolic pulmonary hypertension is one of the most prevalent forms of pulmonary hypertension and is a major complication of acute pulmonary embolism.
Francisca Alexandra Gavilanes-Oleas +9 more
doaj +1 more source
[New oral anticoagulants - influence on coagulation tests]. [PDF]
, 2014 The new oral anticoagulants (NOACs) represent alternative antithrombotic agents for prophylaxis and therapy of thromboembolic diseases. They act either by inhibition of the clotting factor Xa or IIa (thrombin).
Simeon, L +2 more
core +1 more source