Results 11 to 20 of about 1,538,497 (307)
NEW ORAL ANTICOAGULANTS: FOCUS ON THE SAFETY [PDF]
Рациональная фармакотерапия в кардиологии, 2015 Comparative analysis of oral anticoagulants (vitamin K antagonists and new drugs, including dabigatran, rivaroxaban and apixaban) is presented from the standpoint of safety.
D. A. Napalkov, A. A. Sokolova
doaj +2 more sources
The safety of new oral anticoagulants for ischemic stroke and systemic embolism prevention in females with atrial fibrillation [PDF]
Romanian Journal of Neurology, 2021 The prevalence of atrial fibrillation is lower in females than in men, but the risk of stroke and systemic thromboembolism is comparable or even higher. Administration of anticoagulant therapy does not modify this difference. Two classes of non-vitamin K
Despina-Manuela Toader +3 more
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Frontiers in Pharmacology, 2023 Objectives: Our objective was to analyse effectiveness and safety of oral anticoagulants (OAC) for stroke prevention in non-valvular atrial fibrillation.Material and methods: Population-based cohort study including adults initiating oral anticoagulants ...
Maria Giner-Soriano +18 more
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Canadian Medical Association Journal, 2015 A CMAJ letter[1][1] from a “little cheese” family physician about new oral anticoagulants versus warfarin, and the response[2][2] from three “big cheese” academic specialists show that readers and authors of guidelines do not always agree.
Thomas L, Perry +4 more
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Changes in the Gut Microbiota May Affect the Clinical Efficacy of Oral Anticoagulants
Frontiers in Pharmacology, 2022 The mechanism underlying large individual differences in the response to oral anticoagulants has not been fully clarified, and the influence of the intestinal microbiome on exogenous drug metabolism has gradually become an area of increased research ...
Wenjun Chen +13 more
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Atrial Fibrillation, Oral Anticoagulants, and Concomitant Active Cancer: Benefits and Risks
TH Open, 2021 Aim To determine to what extent active cancer influences the benefit–risk relationship among patients with atrial fibrillation receiving oral anticoagulants for stroke prevention.
Adriano Atterman +3 more
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The new oral anticoagulants [PDF]
Clinical Medicine, 2011 Anticoagulants have been used for over 70 years for prevention and treatment of potentially fatal thromboembolic events. Heparins and vitamin K antagonists have been the mainstay of treatment and, although effective if managed properly, also have significant drawbacks. Unfractionated heparins (UFH)
Breen, K. A., Hunt, B. J.
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The new oral anticoagulants [PDF]
Blood, 2010 Abstract Although their first application in clinical practice occurred in the 1940s, vitamin K antagonists remain the only form of oral anticoagulant medication approved for long-term use. Although the available vitamin K antagonists are highly effective for the prevention and/or treatment of most thrombotic disease, the significant ...
David, Garcia +2 more
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PLoS ONE, 2021 BackgroundProton pump inhibitors (PPIs) are known to reduce the risk of upper gastrointestinal bleeding in patients on oral anticoagulants, and patients are increasingly on oral anticoagulants and PPI co-therapy.
Hyun-Jung Lee +7 more
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Effects of oral anticoagulants on bone health (systematic literature review)
Bolʹ, Sustavy, Pozvonočnik, 2023 Background. Osteoporosis is actually today's problem, as it affects the quality and length of life, and increases the risk of fragility fractures, which leads to significant medical, social, and economic problems.
H.V. Mostbauer +4 more
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