Results 11 to 20 of about 1,458,916 (304)
Novel oral anticoagulants [PDF]
Oral anticoagulants have been used widely for the treatment of venous thromboembolism and stroke prevention. The vitamin K antagonists (VKAs), such as warfarin, have been around for the last 65 years and its efficacy as thromboprophylaxis remained largely unchallenged, at least until recently.
C W, Khoo +3 more
openaire +3 more sources
NEW ORAL ANTICOAGULANTS: FOCUS ON THE SAFETY [PDF]
Comparative analysis of oral anticoagulants (vitamin K antagonists and new drugs, including dabigatran, rivaroxaban and apixaban) is presented from the standpoint of safety.
D. A. Napalkov, A. A. Sokolova
doaj +2 more sources
The safety of new oral anticoagulants for ischemic stroke and systemic embolism prevention in females with atrial fibrillation [PDF]
The prevalence of atrial fibrillation is lower in females than in men, but the risk of stroke and systemic thromboembolism is comparable or even higher. Administration of anticoagulant therapy does not modify this difference. Two classes of non-vitamin K
Despina-Manuela Toader +3 more
doaj +1 more source
A CMAJ letter[1][1] from a “little cheese” family physician about new oral anticoagulants versus warfarin, and the response[2][2] from three “big cheese” academic specialists show that readers and authors of guidelines do not always agree.
Thomas L, Perry +4 more
openaire +2 more sources
Objectives: Our objective was to analyse effectiveness and safety of oral anticoagulants (OAC) for stroke prevention in non-valvular atrial fibrillation.Material and methods: Population-based cohort study including adults initiating oral anticoagulants ...
Maria Giner-Soriano +18 more
doaj +1 more source
Oral Anticoagulation Thresholds [PDF]
Background Monitoring patients on oral anticoagulation is essential to prevent hemorrhage and recurrent thrombosis. We studied tissue factor–induced whole-blood coagulation in patients on warfarin therapy with similar international ...
K E, Brummel +3 more
openaire +2 more sources
Is it necessary to alter anticoagulation therapy for tooth extraction in patients taking direct oral anticoagulants? [PDF]
PubMedID: 29053656Background: The number of patients using direct oral anticoagulants (DOACs) instead of vitamin K antagonists (VKA) is increasing and there is limited data on the safety of tooth extractions in patients taking DOACs.
Tükel H.-C. +3 more
core +2 more sources
Novel Bleeding Risk Score for Patients with Atrial Fibrillation on Oral Anticoagulants, including Direct Oral Anticoagulants. [PDF]
OBJECTIVE Balancing bleeding risk and stroke risk in patients with atrial fibrillation (AF) is a common challenge. Though several bleeding risk scores exist, most have not included patients on direct oral anticoagulants (DOAC).
Del Giovane, Cinzia +26 more
core +3 more sources
Changes in the Gut Microbiota May Affect the Clinical Efficacy of Oral Anticoagulants
The mechanism underlying large individual differences in the response to oral anticoagulants has not been fully clarified, and the influence of the intestinal microbiome on exogenous drug metabolism has gradually become an area of increased research ...
Wenjun Chen +13 more
doaj +1 more source
Atrial Fibrillation, Oral Anticoagulants, and Concomitant Active Cancer: Benefits and Risks
Aim To determine to what extent active cancer influences the benefit–risk relationship among patients with atrial fibrillation receiving oral anticoagulants for stroke prevention.
Adriano Atterman +3 more
doaj +1 more source

