Results 211 to 220 of about 59,116 (263)
Hemorrhagic Complications in Patients with Atrial Fibrillation Treated with Novel Oral Anticoagulants: Results from the CRAFT Study. [PDF]
Styczkiewicz M +10 more
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Tailoring Anticoagulant Therapy: Managing Interactions Between Carbamazepine and Direct Oral Anticoagulants (DOACs). [PDF]
Mohammed TH +4 more
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Danazol and Oral Anticoagulants
Scottish Medical Journal, 1982A case report of overt bleeding in a young woman on warfarin given the anabolic steroid danazol for menorrhagia is reported. This interaction appears to be poorly recognised and we suggest that when commencing such a treatment the dose of anticoagulant should initially be halved and thereafter tailored to the thrombotest.
M, Small +4 more
openaire +2 more sources
Pharmacogenetics of oral anticoagulants
Pharmacogenetics, 2003There is wide interindividual variation in oral anticoagulant dose requirement, which is partly genetically determined. Several cytochrome P450s contribute to oxidative metabolism of oral anticoagulants. The most important of these is CYP2C9, which hydroxylates the S-enantiomers of warfarin, acenocoumarol and phenprocoumon with high catalytic activity.
Daly AK, King BP
openaire +3 more sources
Pharmacogenetics of Oral Anticoagulants
Personalized Medicine, 2005Understanding the basis for the observed wide interindividual variation in the dose requirement for the oral anticoagulants should facilitate the safer use of these widely prescribed drugs. Factors that include patient age, body weight and concomitant medications are well known to affect dose requirement and in a large number of recent pharmacogenetic ...
Julio César, Rojas +3 more
openaire +4 more sources
The market for oral anticoagulants
Nature Reviews Drug Discovery, 2018This article discusses the market for oral anticoagulants, and how therapies in development and antidotes to existing drugs could affect the therapeutic landscape.
Stephen, Bielecki +2 more
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