Results 221 to 230 of about 2,176,373 (353)

Effect of hepatic dysfunction and T tube clamping on FK 506 pharmacokinetics and trough concentrations [PDF]

, 1990
Cadoff, E, Fung, JJ, Jain, AB, Krajack, A, Starzl, TE, Todo, S, Venkataramanan, R   +6 more
core  

Penicillin allergy de‐labelling in the critical care unit: Simulations to design an intravenous drug provocation test that mirrors the plasma profile of an enteral challenge

British Journal of Clinical Pharmacology, EarlyView.
The majority of penicillin allergy labels are incorrect and a label of penicillin allergy is associated with worse outcomes and increased use of healthcare services. Penicillin allergy assessment and de‐labelling may be considered in critically ill patients. An oral penicillin challenge is a common component of most penicillin allergy protocols.
Cleodie Swire, Sean Keane, Reya Vinay Shah, Toqa El‐Nahhas, Iao Lei, Salma Alamin, Niall Conlon, Dagan Osborne Lonsdale   +7 more
wiley   +1 more source

Enhancing the Solubility and Oral Bioavailability of Trimethoprim Through PEG-PLGA Nanoparticles: A Comprehensive Evaluation of In Vitro and In Vivo Performance. [PDF]

Pharmaceutics
Zhou Y, Dai G, Xu J, Xu W, Li B, Chen S, Zhang J.   +6 more
europepmc   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

Enhancement of oral bioavailability of risedronate through xyloglucan rafts. [PDF]

J Pharm Pharm Sci
Namazi NI, Bafail R, Alanezi AA, Almuqati AF, Alshammari MS, Alghamdi MA.   +5 more
europepmc   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Butyrate-based ionic liquid for improved oral bioavailability and synergistic anti-colorectal cancer activity of glycyrol. [PDF]

J Pharm Anal
Wang Z, Shi X, Shu Y, Gao R, Sun T, Wu M, Dong M, Wu W, Ma R, Tang D, Ye M, Ji S.   +11 more
europepmc   +1 more source

Antioxidant, Anti-Inflammatory, and Oral Bioavailability of Novel Sulfonamide Derivatives of Gallic Acid. [PDF]

Antioxidants (Basel)
Alhyari D, Qinna NA, Sheldrake HM, Kantamneni S, Ghanem BY, Paluch KJ.   +5 more
europepmc   +1 more source

Electro-encephalographic surrogate measures fail to describe the pharmacodynamic interaction between ketamine and propofol. [PDF]

, 2004
Mortier, Eric, Struys, Michel, VEREECKE, HUGO   +2 more
core   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source