Results 91 to 100 of about 4,901,377 (308)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Estimating the burden of care for oral potentially malignant disorders and oral cancer in Brazilian dental practice

Oral cancer (OC) and oral potentially malignant disorders (OPMD) pose significant challenges to public health in Brazil. This study aimed to estimate the prevalence of oral cancer (OC) and oral potentially malignant disorders (OPMD) among patients who ...
Kowalski, Luiz Paulo, Lopes, Marcio Ajudarte, Ribeiro, Ana-Carolina-Prado, Migowski, Arn, Dos Santos, Erison Santana, de Paiva, João Paulo Gonçalves, Warnakulasuriya, Saman, Brandao, Thais-Bianca, de Paiva, João Paulo Gonçalves, Lopes, Márcio Ajudarte, Cohen-Goldemberg, Daniel, Migowski, Arn, Jorge, Jacks, Kowalski, Luiz Paulo, Jorge, Jacks, da Silva, Eurípides Alves [UNESP], Santos-Silva, Alan Roger, Vargas, Pablo Agustin, Vargas, Pablo, Cohen-Goldemberg, Daniel, Ribeiro, Ana Carolina Prado, dos Santos, Erison-Santana, Brandão, Thaís Bianca   +22 more
core   +1 more source

Functional profiling of the oral microbiome reveals microbial and oncogenic signatures in never-smoking female patients with oral squamous cell carcinoma

Journal of Oral Microbiology
Background The pathogenesis of oral squamous cell carcinoma (OSCC) in never-smoking females remains poorly understood, as these patients lack traditional risk factors.
Sung Min Kim, Zeba Praveen, Yeon-Hee Kim, Jae Hee Ko, Yong-Seok Choi, Joo Yong Park, Jong Ho Lee, Sung Weon Choi, Mi Kyung Kim   +8 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Genes and oral cancer

Indian Journal of Human Genetics, 2014
Oral cancers have been one of the leading causes of deaths particularly in the developing countries. Prime reason for this high mortality and morbidity is attributed to the delay in diagnosis and prompt treatment. Relentless research in the field of oncology has led to the advent of novel procedures for the early detection of oral cancers.
Jurel, Sunit Kumar, Gupta, Durga Shanker, Singh, Raghuwar D., Singh, Mrinalini, Srivastava, Shilpi   +4 more
openaire   +3 more sources

Per-oral cross-facial sural nerve graft for facial reanimation

Maxillofacial Plastic and Reconstructive Surgery, 2018
Background Cross-facial nerve graft is considered the treatment of choice for facial reanimation in patients with unilateral facial palsy caused by central facial nerve damage.
Joohee Jeong, Akram Abdo Almansoori, Hyun-Soo Park, Soo-Hwan Byun, Seung-Ki Min, Han-Wool Choung, Joo Yong Park, Sung Weon Choi, Bongju Kim, Soung-Min Kim, Jong-Ho Lee   +10 more
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Investigation of the minimum uptake time for quantitative jawbone SPECT

BMC Oral Health
Background The range of imaging times recommended for bone scintigraphy is wide, and uptake times vary across facilities. In our previous quantitative evaluation of jawbone SPECT using [99mTc] Tc-HMDP, we reported that standardized uptake values at the 2-
Hironobu Hata, Kenji Hirata, Satoshi Shimomura, Kenji Imamachi, Takuya Asaka, Mayumi Kamaguchi, Kenta Miwa, Masashi Matsuzaka, Yoichi Mori, Toshikazu Nambu   +9 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source