Results 171 to 180 of about 587,078 (311)

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

open access: yesAdvanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia   +29 more
wiley   +1 more source

Experimental and clinical evaluation of the local therapy with solid and oil bleomycin for the oral cancer

open access: bronze, 1977
Masahito Sugimura   +8 more
openalex   +2 more sources

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz   +14 more
wiley   +1 more source

Studies on cell-mediated immune responses in oral cancer patients

open access: bronze, 1979
Takashi FUJIBAYASHI   +5 more
openalex   +2 more sources

Oral cancer: Who best to detect oral cancer? [PDF]

open access: yesBritish Dental Journal, 2015
Darren Owens   +2 more
openaire   +3 more sources

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

open access: yesAdvanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji   +12 more
wiley   +1 more source

Oral contraceptives and risk of ovarian cancer

open access: bronze, 1981
Walter C. Willett   +4 more
openalex   +1 more source

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