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Notch signaling in oral pre-cancer and oral cancer

Medical Oncology, 2021
Notch signaling involves cell to cell contact. It is an ancient signaling mechanism that is conserved throughout the animal kingdom. The basic function of Notch signaling is to decide cell fate and execute asymmetrical division. Notch signaling is indispensable for embryo growth.
Kumud Nigam, Ratnesh Kumar Srivastav
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Candida in oral pre-cancer and oral cancer

Medical Hypotheses, 2011
Oral pre-malignancies and carcinomas are common epithelial pathologies caused by a variety of etiological factors. In the oral cavity, candidiasis is the most frequent opportunistic fungal infection. Since the initial reports of an association between candidiasis with oral pre-cancer and cancer, various theories have been debated regarding the role of ...
P R, Sanjaya   +3 more
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The Oral Microbiome and Oral Cancer

Clinics in Laboratory Medicine, 2014
The role that bacteria play in the etiology and predisposition to cancer is of increasing interest, particularly since the development of high-throughput genetic-based assays. With this technology, it has become possible to comprehensively examine entire microbiomes as a functional entity.
Laura, Wang, Ian, Ganly
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The Treatment of Oral Cancer [PDF]

open access: yesCa-A Cancer Journal for Clinicians, 1972
Richard H Jesse
exaly   +3 more sources

Oral Cancer

Mayo Clinic Proceedings, 2007
Five percent of all tumors occur in the head and neck, and approximately half of those occur specifically in the oral cavity. Of the 615,000 new cases of head and neck [corrected] tumors reported worldwide in 2000, 300,000 were primary oral cavity squamous cell carcinomas. Recent data from the Surveillance, Epidemiology, and End Results Program suggest
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The pathology of oral cancer

Pathology, 2003
Oral cancer is a serious public health problem, with over 200,000 new cases reported annually worldwide, two-thirds of which occur in developing countries. The overall mortality rate for intra-oral cancer remains high at approximately 50%, even with modern medical services, probably due to the advanced stage of the disease at presentation.
D Murray, Walker   +2 more
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Oral Cancer

Critical Reviews in Oral Biology & Medicine, 1990
In the U.S. oral cancer accounts for 2.1% of all cancers and 1% of cancer deaths. Two to three times as many males as females are affected. Blacks have more intra-oral cancer than whites, and their incidence and mortality rates have increased in recent years. The etiologic process very likely involves several factors.
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Salivaomics in oral cancer

Current Opinion in Otolaryngology & Head & Neck Surgery, 2019
Purpose of review The goal of cancer screening is to detect tumor at an early stage, and early cancer detection is the hallmark of successful treatment. In addition to traditional tissue biopsy-based diagnostics, more reliable, inexpensive, and noninvasive methods are required for early diagnosis of cancer.
Aro, Katri   +2 more
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Telomerase and oral cancer

Oral Oncology, 2001
The development of malignant neoplasms is a multistep process and it is believed that multiple genetic alterations are involved. The progression of neoplastic lesions is also characterized by reactivation of telomerase, a ribonucleoprotein complex enzyme that adds telomere repeats at the ends of chromosomes.
T, Sumida, H, Hamakawa
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