Results 41 to 50 of about 63,840 (254)

FUNGAL DISEASE OF THE ORAL CAVITY

Медицинский совет, 2017
The problem of oral candidiasis is topical for the adult population and children due to frequent recurrence, the presence of a large number of predisposing factors, lack of compliance with hygienic measures for the care of the oral cavity.
L. N. DROBOTKO, L. P. KISELNIKOVA, A. G. SEDOYKIN, I. A. DRONOV   +3 more
doaj   +1 more source

Gaining insights from Candida biofilm heterogeneity: one size does not fit all [PDF]

, 2018
Despite their clinical significance and substantial human health burden, fungal infections remain relatively under-appreciated. The widespread overuse of antibiotics and the increasing requirement for indwelling medical devices provides an opportunistic ...
Delaney, Christopher, Kean, Ryan, McLean, William, Metcalfe, Rebecca, Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Thomas, Rachael, Williams, Craig   +8 more
core   +4 more sources

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

A pseudo-randomised clinical trial of in situ gels of fluconazole for the treatment of oropharngeal candidiasis [PDF]

, 2011
Background Oropharyngeal candidasis is a common opportunistic infection seen in immunocompromised patients. Fluconazole has a broad spectrum antifungal activity including a wide variety of candida species.
Harish M Nairy, Narayana R Charyulu, Veena A Shetty, Prabhu Prabhakara, Nairy, Harish M   +4 more
core   +2 more sources

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

A study on the management of corticosteroid side effects in cancer patients [PDF]

, 2015
Background Systemic corticosteroids lead to many adverse effects especially in cancer patients. Preventive measures and treatment options are essential to minimise such side effects.
Fsadni, Clayton John
core  

Extracellular aspartic protease SAP2 of Candida albicans yeast cleaves human kininogens and releases proinflammatory peptides, Met-Lys-bradykinin and des-Arg(9)-Met-Lys-bradykinin [PDF]

, 2012
Bradykinin-related peptides, universal mediators of inflammation collectively referred to as the kinins, are often produced in excessive amounts during microbial infections.
Alexander Faussner, Andrzej Kozik, Barbasz, Carvalho, Gomes, Grazyna Bras, Ibeth Guevara-Lora, Kraus, Laemmli, Leeb, Maria Rapala-Kozik, Oehmcke, Oliwia Bochenska, Reddigari, Sainz, Sato, Zubakova   +16 more
core   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Salivary iron and Candida colonization in oral lichen planus patients undergoing topical steroid therapy

BMC Oral Health
Background The most common adverse event in oral lichen planus (OLP) patients undergoing topical corticosteroid therapy is opportunistic infection with oral Candida.
Auranat Prachayakul, Jeerus Sucharitakul, Jaranya Chadsiri, Chanwit Prapinjumrune   +3 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source