Results 171 to 180 of about 1,874,188 (207)

Embracing Oral Cholera Vaccine — The Shifting Response to Cholera

New England Journal of Medicine, 2014
Despite evidence of the safety and efficacy of oral cholera vaccines, they were not included in the prevention package during the 2010 Haitian cholera epidemic. But some major obstacles to the use of OCVs in cholera outbreaks have since been overcome.
Jean W Pape, Vanessa Rouzier
exaly   +3 more sources

Live Attenuated Oral Cholera Vaccines

Expert Review of Vaccines, 2006
Live, orally administered, attenuated vaccine strains of Vibrio cholerae have many theoretical advantages over killed vaccines. A single oral inoculation could result in intestinal colonization and rapid immune responses, obviating the need for repetitive dosing. Live V.
Stephen B Calderwood, Firdausi Qadri, Edward Thomas Ryan   +2 more
exaly   +3 more sources

PaxVax CVD 103-HgR Single-Dose Live Oral Cholera Vaccine

Expert Review of Vaccines, 2017
Introduction: Cholera remains a problem in developing countries and a risk for travelers. Hypochlorhydria, blood group O, cardiac and renal disease increase the risk of developing cholera gravis.
Wilbur H Chen, Myron Levine, James B. Kaper   +2 more
exaly   +2 more sources

Oral Cholera Vaccines

Lancet, The, 1986
exaly   +4 more sources

Field Trial of Oral Cholera Vaccines in Bangladesh.

Lancet, The, 1986
The protective efficacy of oral B subunit killed whole-cell (BS-WC) and killed whole-cell (WC) cholera vaccines was assessed in 63 498 Bangladeshi children aged 2-15 years and women aged over 15 years. Each received three doses of BS-WC, WC, or placebo in a randomised, double-blinded fashion. Surveillance for cases seeking medical care up to six months
John David Clemens, David A. Sack, Mohammed Yunus   +2 more
exaly   +4 more sources

Field Trial of Oral Cholera Vaccine in Vietnam

Lancet, The, 1997
John David Clemens
exaly   +3 more sources

Oral cholera vaccines: use in clinical practice

The Lancet Infectious Diseases, 2006
Cholera continues to occur globally, particularly in sub-Saharan Africa and Asia. Oral cholera vaccines have been developed and have now been used for several years, primarily in traveller populations. The licensure in the European Union of a killed whole cell cholera vaccine combined with the recombinant B subunit of cholera toxin (rCTB-WC) has ...
David R, Hill, Lisa, Ford, David G, Lalloo   +2 more
openaire   +2 more sources

A Prototype Live Oral Cholera Vaccine

Nature, 1971
Using the methods of molecular genetics it should be possible to develop a cholera vaccine that produces long lasting immunity. To this end Vibrio cholerae mutants deficient in choleragenic activity have been isolated.
openaire   +2 more sources

Live oral vaccines against cholera: An update

Vaccine, 1993
One hundred years elapsed between the first (live, parenteral) cholera vaccine that entered clinical trials in 1885 and the field trials of two oral inactivated cholera vaccines undertaken in Bangladesh in the mid-1980s. The oral inactivated vaccines advanced the art by establishing, convincingly, that oral vaccines could protect (although multiple ...
M M, Levine, J B, Kaper
openaire   +2 more sources

Oral vaccines for cholera control.

The National medical journal of India, 1997
Two oral cholera vaccines-inactivated WC/rBS and live CVD 103 HgR-have recently been marketed in Europe. Though the efficacy of the live vaccine is yet to be supported by field trials, the inactivated oral vaccine has shown encouraging results in field trails on different population groups.
S, Chaturvedi, S, Chaturvedi
openaire   +1 more source