Results 91 to 100 of about 117,738 (304)

Navigating the Post‐BCMA/GPRC5D Landscape: Efficacy of Selinexor, Bortezomib, and Dexamethasone After Sequential Immunotherapy Failure in Penta‐Refractory Multiple Myeloma—A Multicenter Analysis

American Journal of Hematology, EarlyView.
ABSTRACT Patients with relapsed/refractory multiple myeloma (RRMM) who are penta‐drug refractory, defined as resistant to two proteasome inhibitors, two immunomodulatory agents, and an anti‐CD38 monoclonal antibody, face a dismal prognosis, particularly after exposure to T‐cell–redirecting therapies.
Maximilian Al‐Bazaz, Winfried Alsdorf, Lisa Leypoldt, Piet Sonnemann, Christoph Schaefers, Jule Artzenroth, Marie Harzer, Abdulaziz Kamili, Leandra Bartke, Leon Cords, Jan Vorwerk, Theo Leitner, Markus Maulhardt, Kerstin Brinkert, Annamaria Brioli, Tim Richardson, Udo Holtick, Stefan M. Hillmann, Hans Salwender, Cyrus Khandanpour, Carsten Bokemeyer, Katja Weisel, Ricardo Kosch   +22 more
wiley   +1 more source

Evaluation of extended and continuous use oral contraceptives

Therapeutics and Clinical Risk Management, 2008
Kristen Page Wright, Julia V JohnsonUniversity of Vermont College of Medicine and Reproductive Endocrinology and Infertility, Women’s Health Care Services, Fletcher Allen Health Care, Burlington, VT USAAbstract: Oral contraceptives are ...
Kristen Page Wright, Julia V Johnson
doaj  

The Unilateral Enigma: An Oral-contraceptive Related Gingival Enlargement

Journal of Pharmacy and Bioallied Sciences
This article’s goal is to describe a case of oral contraceptives-related drug-induced gingival hypertrophy that was treated with nonsurgical and surgical periodontal therapy. The most prevalent negative side effect of systemic medicine on the periodontal
Balaji Anitha, Jennifer W, Mohanasatheesh S, Hema D, Dheeraj S, Menon Nivedha   +5 more
doaj   +1 more source

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

American Journal of Hematology, EarlyView.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo, Elisa Sambruna, Yoshitaka Miyakawa, Marc Michel, Carlo Visco, Michael Fillitz, George Kannourakis, Maria Bruna Greve, Moritz Kleemiss, Johan Cid, Andrea Patriarca, Laura Pavan, Arbana Dizdari, Nilla Maschio, Antonella Sau, Cinzia Bitetti, Riccardo Mario Colombo, Luigi Curreli, Dorela Lame, Uros Markovic, Fabrizio Pappagallo, Giacinto Luca Pedone, Davide Rapezzi, Vincenzo Sammartano, Nicola Tumedei, Antonio Giovanni Solimando, Jalink Marit, Luana Fianchi, Jahanzaib Khwaja, Antonio De Vivo, Francesco Lanza, Fabrizio Vianello, Esther N. Oliva, Catherine Broome, Francesco Passamonti, Ulrich Jaeger, Bernd Jilma, Guillaume Moulis, Wilma Barcellini   +38 more
wiley   +1 more source

Secular Trends in Age at Menarche, Smoking, and Oral Contraceptive Use Among Israeli Girls

Preventing Chronic Disease, 2005
Introduction The improved nutrition and socioeconomic status of the population in industrialized countries has resulted in a decrease in the mean age at menarche.
Ran D. Balicer, MD, Nadav Davidovitch, MD, MPH, Itamar Grotto, MD, MPH, Michael Huerta, MD, MPH, Gabriel Chodick, PhD, MHA   +4 more
doaj  

Comparative description of the use of modern methods of hormonal contraception for women with excessive body mass

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Maintenance of reproductive health of women with excessive weight is the actual problem of nowadays and is an important direction of modern medicine. Aim.
I. B. Gridina
doaj   +1 more source

Oral Contraceptives and User Satisfaction in Kanchanaburi, Thailand [PDF]

This study aims to identify the factors that affect women who use public and private oral contraceptive services. It also aims to assess user satisfaction among pill users, particularly those who are covered by the 30-Baht card of the Universal Coverage ...
Kusol Soonthorndhada, Tiwarat Tor.Jarern
core  

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco, Alfonso Manuel D'Alessio, Nicola Brunetti‐Pierri   +2 more
wiley   +1 more source

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

Animal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat, Chatsuree Suksamai, Dhammika Leshan Wannigama, Kent Doi, Wiwat Chancharoenthana, Asada Leelahavanichkul   +5 more
wiley   +1 more source

Influence of combined oral contraceptives on the periodontal condition

Journal of Applied Oral Science, 2012
Most studies investigating the impact of oral contraceptives have been performed some years ago, when the level of sexual hormones was greater than the actual formulations.
Roberta Santos Domingues, Bruna Fidêncio Rahal Ferraz, Sebastião Luiz Aguiar Greghi, Maria Lúcia Rubo de Rezende, Euloir Passanezi, Adriana Campos Passanezi Sant’Ana   +5 more
doaj   +1 more source