Results 11 to 20 of about 200,531 (312)

COPD: an inhaled corticosteroid-resistant, oral corticosteroid-responsive condition [PDF]

European Respiratory Journal, 2006
To the Editors: Few areas of respiratory medicine have generated as much controversy as the use and purpose of long-term corticosteroid treatment in chronic obstructive pulmonary disease (COPD). However, several recent large, placebo-controlled studies have clarified the role of long-term treatment with inhaled corticosteroids 1–3.
Saha, S, Siva, R, Brightling, CE, Pavord, ID   +3 more
openaire   +3 more sources

Association Between Baseline Therapy and Flare Reduction in Mepolizumab-Treated Patients With Hypereosinophilic Syndrome

Frontiers in Immunology, 2022
BackgroundCurrent standard-of-care treatments for hypereosinophilic syndrome (HES) include oral corticosteroids (OCS) and immunosuppressive/cytotoxic (IS/CT) therapies.
Andreas Reiter, Guillaume Lefevre, Maria C. Cid, Namhee Kwon, Eleni Mavropolou, Steven W. Yancey, Jonathan Steinfeld   +6 more
doaj   +1 more source

Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines—an exploratory study [PDF]

, 2013
<p>Background: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear.
A McKay, A Sykes, B Pedersen, Carl de Wet, Charles McSharry, Christopher J. Weir, E Goleva, E Goleva, E Irusen, E Juniper, E Livingston, GJ Zijlstra, GW Chalmers, GW Chalmers, H Kerstjens, J Kam, J St-Laurent, JEM Tomlinson, M Althuis, M Broekema, M Spears, Marco Idzko, Mark Spears, MR Edwards, MR Miller, MR Stämpfli, NC Thomson, Neil C. Thomson, R Chaudhuri, R Chaudhuri, R Crapo, R Meijer, R Sher, Rekha Chaudhuri, S Holgate, SC Lazarus, SE Pedersen, SE Wenzel, WE Naugler, Z Qiu, Z Xing   +40 more
core   +11 more sources

Use of Oral Corticosteroids and Risk of Hip Fracture in the Elderly in a Case-Control Study

Frontiers in Pharmacology, 2017
Aim: Little is known regarding the relationship between use of oral corticosteroids and hip fracture in the elderly in Taiwan. The aim of the study was to examine this issue.Methods: A retrospective population-based case-control study using the database ...
Shih-Wei Lai, Shih-Wei Lai, Cheng-Li Lin, Cheng-Li Lin, Kuan-Fu Liao, Kuan-Fu Liao, Kuan-Fu Liao   +6 more
doaj   +1 more source

Steroids in pediatric eosinophilic esophagitis [PDF]

, 2014
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core   +1 more source

Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development [PDF]

, 2005
This study aimed to test the utility of the ozone challenge model for profiling novel compounds designed to reduce airway inflammation. The authors used a randomized, doubledummy, double-blind, placebo-controlled 3-period crossover design alternating ...
Gibson, Anthony, Holz, Olaf, Janicki, Stanislawa, Jörres, Rudolf A., Kanniess, Frank, Magnussen, Helgo, Richter, Kai, Simpson, Kathy J., Tal-Singer, Ruth, Vessey, Rupert S. J.   +9 more
core   +1 more source

Study of effect of inhaled versus oral corticosteroids on sputum granzyme B in patients with moderate persistent bronchial asthma

Egyptian Journal of Chest Disease and Tuberculosis, 2015
Background: Asthma is a major public health problem with a high economic burden. It involves several inflammatory cells and multiple mediators. Granzyme B is an inflammatory mediator expressed and secreted by both immune and non immune cells. Recently it
Walaa K. Shoeib, Mahmoud M. Alsalahy, Mohammad A. Almahdy, Tarek S. Essawy, Khalid M. Belal   +4 more
doaj   +1 more source

Kaposi's sarcoma in a patient with erythroblastopenia and thymoma: Reactivation after topical corticosteroids [PDF]

, 1998
We report a 69-year-old female with erythroblastopenia and thymoma who developed lesions of Kaposi's sarcoma (KS) after thymectomy, 2 months after the initiation of therapy with methylprednisolone.
Alomar, A., Barnadas, M. A., Curell, R., de Moragas, J. M., Garcia-Patos, V., Kind, P., Pedro, C., Perez, E., Sander, C. A.   +8 more
core   +1 more source

Corticosteroids for the common cold [PDF]

, 2015
BACKGROUND: The common cold is a frequent illness, which, although benign and self limiting, results in many consultations to primary care and considerable loss of school or work days. Current symptomatic treatments have limited benefit.
Del Mar, Chris B., Glasziou, Paul P., Hayward, Gail, Heneghan, Carl J., Perera, Rafael, Thompson, Matthew J.   +5 more
core   +1 more source

Oral Corticosteroid Use and the Risk of Acute Myocardial Infarction in Chronic Obstructive Pulmonary Disease

Canadian Respiratory Journal, 2006
BACKGROUND: Given the limited efficacy of oral corticosteroids in treating chronic obstructive pulmonary disease (COPD), the possible cardiac side effects of oral corticosteroids are of particular concern in an elderly population.
Laetitia Huiart, Pierre Ernst, Xavier Ranouil, Samy Suissa   +3 more
doaj   +1 more source