Results 61 to 70 of about 4,484,225 (267)

Dosage compensation in birds [PDF]

, 2001
The Z and W sex chromosomes of birds have evolved independently from the mammalian X and Y chromosomes [1]. Unlike mammals, female birds are heterogametic (ZW), while males are homogametic (ZZ).
Bird, Adrian P, Derek McBride, McQueen, H A; id_orcid, Gino Miele, McQueen, Heather A, McBride, Derek, Miele, Gino, McBride, D, Miele, G, Clinton, M, Bird, A P; id_orcid, Heather A McQueen, Michael Clinton, Clinton, Michael, Adrian P Bird   +14 more
core   +1 more source

Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube

Journal of Pharmaceutical Research, 2023
Solid dosage forms like modified release and enteric coated formulations are considered inappropriate for nasogastric feeding tube (NGFT) administration due to varying pharmacokinetics which could lead to inadequate therapeutic responses or ...
L A Pradeep Rajkumar, Sujith J Chandy, Heber Rew Bright, V J Hema Jiji, Judith Basker, K Gunaraj   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Understanding the Multidimensional Effects of Polymorphism, Particle Size and Processing for D-Mannitol Powders

Pharmaceutics, 2022
The relevance of the polymorphic form, particle size, and processing of mannitol for the mechanical properties of solid oral dosage forms was examined. Thus, particle and powder properties of spray granulated β D-mannitol, β D-mannitol, and δ D-mannitol ...
Lena Mareczek, Carolin Riehl, Meike Harms, Stephan Reichl   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Ayurvedic Dosage Forms: Pressing Priorities and Challenges therein with Respect to Solid and Semisolid Oral Dosage Forms

Indian Journal of Ayurveda and Integrative Medicine KLEU
Continuous improvements in elevating traditional dosage forms to increase therapeutic efficacy, to enable patient-centric approaches, and to improve patient compliance are becoming more rational with advancements in technology and an advanced vision to ...
Sakshi Badyal, Poonam Dang, Puneet Dhawan, Himanshu Shekhar Tiwari   +3 more
doaj   +1 more source

Consumer Preferences and Perceptions towards the use Colored Oral Solid Dosage Forms in Baghdad [PDF]

Archives of Pharmacy Practice, 2010
Objective: The main aims of this study were to determine consumers’ preferences and perceptions in Baghdad towards the color of Oral Solid Dosage Form.Materials and Methods: A cross sectional study was conducted using a self–administered questionnaire. A
Inas Rifaat Ibrahim,*, Mohamed Izham M.I & Mahmoud Al-Haddad
doaj  

3DP Printing of Oral Solid Formulations: A Systematic Review

Pharmaceutics, 2021
Three-dimensional (3D) printing is a recent technology, which gives the possibility to manufacture personalised dosage forms and it has a broad range of applications.
Chiara R. M. Brambilla, Ogochukwu Lilian Okafor-Muo, Hany Hassanin, Amr ElShaer   +3 more
doaj   +1 more source

Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022
Due to the lack of age-appropriate formulations for children, healthcare professionals and caregivers frequently manipulate dosage forms to facilitate oral administration and obtain the required dose.
Jenny Johannesson, P. Hansson, Christel A. S. Bergström, M. Paulsson   +3 more
semanticscholar   +1 more source