Results 81 to 90 of about 6,104,462 (286)

Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma [PDF]

open access: yesISRN Oncology, 2012
Oral cancer is one of the drastic human cancers due to its aggressiveness and high mortality rate. Of all oral cancers, squamous cell carcinoma is the most common accounting for more than 90%. Epithelial-mesenchymal transition (EMT) is suggested to play an important role during cancer invasion and metastasis.
Suttichai Krisanaprakornkit   +1 more
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Hydrogen peroxide contributes to the epithelial cell death induced by the oral mitis group of streptococci. [PDF]

open access: yesPLoS ONE, 2014
Members of the mitis group of streptococci are normal inhabitants of the commensal flora of the oral cavity and upper respiratory tract of humans. Some mitis group species, such as Streptococcus oralis and Streptococcus sanguinis, are primary colonizers ...
Nobuo Okahashi   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Candida spp. adherence to oral epithelial cells and levels of IgA in children with orthodontic appliances

open access: yesBrazilian Oral Research, 2014
Adhesion and colonization of the oral cavity by Candida albicans is an initial step in candidosis. Orthodontic and other oral appliances seem to favor candidal presence. The aim of this work was to compare the presence of Candida species in saliva, their
Célia Regina Gonçalves e Silva   +3 more
doaj   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

open access: yesAdvanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull   +11 more
wiley   +1 more source

An experimental study of the infection of oral mucosa in vitro by candida. [PDF]

open access: yes, 1978
PhDA sequential study of the invasion of oral mucosa by C. albicans is difficult to accomplish in human beings or in animal models. An in vitro model of oral candidal infection has therefore been established and evaluated by light and electron ...
Howlett, Julie Antoinette
core   +4 more sources

Immunoexpression of cytokeratin 19 in oral cavity mucous smear of filter cigarette smokers

open access: yesPadjadjaran Journal of Dentistry, 2008
Smoking has become general habits in social life. One popular kind is filtered cigarette. As the base component is tobacco without clove and separated by the filter on it.
Isra Meira   +2 more
doaj   +1 more source

Cow Milk and Intestinal Epithelial Cell-derived Extracellular Vesicles as Systems for Enhancing Oral Drug Delivery

open access: yesPharmaceutics, 2020
Ingestion is the preferred way for drug administration. However, many drugs have poor oral bioavailability, warranting the use of injections. Extracellular vesicles (EVs) from cow milk have shown potential utility in improving oral drug bioavailability ...
Greta Carobolante   +3 more
doaj   +1 more source

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