Results 91 to 100 of about 1,813,651 (244)

Immunohistochemical expression of PCNA, p53, bax and bcl-2 in oral lichen planus and epithelial dysplasia.

, 2009
The potential for malignant transformation of oral lichen planus is still controversial. The expression of proteins related to cell proliferation and apoptosis in oral lichen planus and epithelial dysplasia was analyzed to evaluate the true potential for
Rosa, Luiz E B, Paradella, Thaís C, Carvalho, Yasmin R, Sousa, Fernando A C G de   +3 more
core   +1 more source

Oral HPV-associated dysplasia: is koilocytic dysplasia a separate entity?

Frontiers in Oral Health
Oral epithelial dysplasia associated with high-risk HPV infection has received different names since its initial description, such as oral Bowenoid lesions, HPV-associated intraepithelial neoplasia, and oral koilocytic dysplasia.
Gabriela Anaya-Saavedra, Marcela Vázquez-Garduño   +1 more
doaj   +1 more source

EffiSegNet: Advances in Automated Segmentation of Actinic Cheilitis and Lip Squamous Cell Carcinoma in Clinical Photographs

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Actinic cheilitis (AC) is a potentially malignant oral disorder linked to lip squamous cell carcinoma (LSCC). Clinical diagnosis is hindered by lesion heterogeneity. While AI tools have shown promise in oral lesion detection and diagnosis, image segmentation remains underexplored. This study developed and externally validated a deep
Vitor Simbalista Teixeira Soares, Anna Luíza Damaceno Araújo, Ivan José Correia‐Neto, Cristina Saldivia‐Siracusa, Raísa Sales de Sá, Hugo Abritta Reis, Ayrton da Costa Ganem Filho, André Carlos Ponce de Leon Ferreira de Carvalho, Thierry Urruty, Paulo Rogério Ferreti Bonan, Nathalia Rodrigues Gomes, Felipe Paiva Fonseca, Pablo Agustin Vargas, Alan Roger Santos‐Silva, Luiz Paulo Kowalski, Matheus Cardoso Moraes, Marcio Ajudarte Lopes   +16 more
wiley   +1 more source

Effect of smoking on MUC1 expression in oral epithelial dysplasia, oral cancer, and irradiated oral epithelium

, 2022
Objectives: The aim of this study was to assess the MUC1 expression in the oral epithelium of normal, oral epithelial dysplasia (OED), oral squamous cell carcinoma (OSCC), and irradiated oral epithelium (IROE) and its association with smoking habits in ...
Schulten, Engelbert A. J. M., Mikkonen, Jopi J.W., Dekker, Hannah, Bhardwaj, Tulika, Kullaa, Arja M., Kashyap, Bina, Bloemena, Elisabeth, Mikkonen, Jopi J. W., Schulten, Engelbert A.J.M.   +8 more
core   +1 more source

Integrated profiling reveals polarity protein dysregulation during oral cancer progression

Scientific Reports
Malignant transformation of oral precancerous lesions is a multistep process intricately linked to the disruption of epithelial cell polarity and activation of the epithelial–mesenchymal transition (EMT) program.
Sandip Ghose, U. Renuka Chaudry, Shouvik Chakravarty, Snehanjan Sarangi, Nidhan K. Biswas, Rathindranath Baral, Debarati Ray   +6 more
doaj   +1 more source

Long‐Term Care of OLP Patients: A Retrospective Study From a Single Hospital Outpatient Clinic

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral lichen planus (OLP) is a chronic immune‐mediated disorder with malignant potential. However, its real‐world clinical course remains incompletely characterized. This study aimed to describe the natural clinical–histopathological trajectory of OLP in a single tertiary centre and to identify factors associated with dysplasia and ...
F. Scilla, G. Gioco, L. Ferrero, R. Castagnola, A. Zafarone, L. Cimino, M. Tranfa, C. Rupe, C. Lajolo   +8 more
wiley   +1 more source

Histological and Immunohistochemical Characterization of Keratotic White Lesions in the Oral Cavity: A Cross-Sectional Study.

The Egyptian Journal of Histology
Background: Oral keratotic white lesions represent a diverse group of conditions, ranging from benign to possibly malignant disorders. Among these, oral epithelial dysplasia (OED) is a crucial histological marker for assessing the risk of malignant ...
Angom Manitombi Devi, Manish Singh Ahuja, Debasis Bandopadhyay, Divya Shelly, Alok Acharya, subhash B   +5 more
doaj   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

The clinical utility of contemporary oral epithelial dysplasia grading systems

, 2022
Introduction Clinical management of oral potentially malignant disorders relies on accurate histopathological assessment of the presence and grade of oral epithelial dysplasia. While adjunctive laboratory tests have provided useful prognostic information,
Peter J. Thomson, Sloan, Philip, Thomson, Peter J., Sathasivam, Hans Prakash, Robinson, Max, Philip Sloan, Hans Prakash Sathasivam, Max Robinson   +7 more
core   +1 more source

Metagenomic Evaluation of Oral Microbiota in Patients Affected by Oral Lichen Planus: A Pilot Study

Oral Diseases, EarlyView.
ABSTRACT Objective To characterize the oral bacterial and fungal microbiota of symptomatic oral lichen planus patients undergoing topical corticosteroid therapy and to explore microbial patterns potentially associated with subsequent oral candidiasis. Methods Twelve patients with clinically and histologically confirmed OLP were enrolled.
A. Dormiente, L. Mancabelli, M. Ventura, G. Longhi, G. Mergoni, M. Manfredi   +5 more
wiley   +1 more source