Results 171 to 180 of about 1,433,667 (207)

Unintentional Weight Loss Does Not Predict Poor Outcomes in Zenker Diverticulum

The Laryngoscope, EarlyView.
In this study of 427 patients with Zenker's diverticulum, 23.6% had significant unintentional preoperative weight loss. Weight loss was associated with preoperative dysphagia and with both the smallest and largest pouches. Postoperative outcomes were similar in patients with and without weight loss, demonstrating a similar efficacy and safety profile ...
Ari D. Schuman, Jacqui Allen, Mekibib Altaye, Milan R. Amin, Semirra L. Bayan, Peter C. Belafsky, Brad W. DeSilva, Shumon I. Dhar, Dale C. Ekbom, Aaron D. Friedman, Mark Fritz, Glendon M. Gardner, Elizabeth A. Guardiani, Christopher Johnson, Jan Kasperbauer, Brandon Kim, Brittany N. Krekeler, Maggie A. Kuhn, Yue Ma, Lyndsay L. Madden, Laura Matrka, Ross M. Mayerhoff, Cyrus Piraka, Apoorva Ramaswamy, Clark A. Rosen, Haley C. Sibley, Meredith Tabangin, Carter Wright, Z. Mike Yang, Vyvy N. Young, Gregory Postma, Rebecca J. Howell   +31 more
wiley   +1 more source

Impact of Frailty on Surgical Outcomes in Patients Treated for Cricopharyngeus Muscle Dysfunction

The Laryngoscope, EarlyView.
ABSTRACT Objective To investigate the relationship between frailty status and surgical outcomes in patients undergoing procedures for cricopharyngeus muscle dysfunction (CPMD). Methods Retrospective chart review of all patients who underwent upper esophageal sphincter (UES) interventions at a tertiary dysphagia center.
Jessa Letargo, Ramey Kharfan, Charmaine Szalay‐Anderson, Derrick R. Randall   +3 more
wiley   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang, William I. Jaffe, Ariana L. Smith   +2 more
wiley   +1 more source

Multifaceted burden of short bowel syndrome for patients and caregivers: The landmark survey

Nutrition in Clinical Practice, EarlyView.
Abstract Background Short bowel syndrome is a debilitating condition often requiring long‐term parenteral support to maintain hydration, nutrition, and survival. Methods As part of the noninterventional, cross‐sectional Landmark Survey study, we evaluated burdens associated with short bowel syndrome and parenteral support dependency from patient and ...
Jenny E. Harrison, Syed‐Mohammed Jafri, Roopa Vemulapalli, Vanessa Kumpf, Gail Mitchell, Mena Boules, Mindy M. Yang, Laurin Jackson, Jinyi Wang, Laurie Zografos, Daniel Wolin, Marion F. Winkler   +11 more
wiley   +1 more source

Management of ketogenic diet therapy in patients with ileostomy: A report of 2 cases

Nutrition in Clinical Practice, EarlyView.
Abstract This case series explores the feasibility and clinical considerations of implementing the ketogenic diet therapy (KDT) for epilepsy management in patients with ileostomies. Two pediatric patients with medication‐resistant epilepsy and ileostomies continued KDT under clinical supervision.
Braden J. Baker, Abigail E. Olbina, Marissa A. Godfrey, Annie E. Graber, Taylor N. Parrish, Sarah Isis R. Delima   +5 more
wiley   +1 more source

Comparison of six nutritional screening tool‐based Global Leadership Initiative on Malnutrition criteria models for predicting activities of daily living in older patients with subacute stroke: A single‐center retrospective cohort study

Nutrition in Clinical Practice, EarlyView.
Abstract Background The Global Leadership Initiative on Malnutrition (GLIM) recommends a two‐step diagnostic process consisting of initial screening for malnutrition risk followed by diagnostic assessment. We evaluated the association between GLIM‐defined malnutrition identified using six alternative first‐step screening tools and Functional ...
Shinnosuke Ishida, Ryota Imai, Yu Kitaji, Satoshi Miyano, Yoshiyuki Kawano   +4 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Frailty and Recovery Following Free Flap Reconstruction in Head and Neck Cancer: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To review the impact of frailty on various outcomes in geriatric head and neck cancer (HNC) patients undergoing microvascular free flap reconstruction (MFFR). Data Sources MEDLINE, Embase, and World of Science. Review Methods Following PRISMA guidelines, two independent reviewers performed a systematic review of MEDLINE, Embase, and ...
Anvitha R. Metpally, Mitchell T. Victor, Mirian Ramirez, Avinash Mantravadi, Michael W. Sim, Michael G. Moore, Jessica A. Yesensky, Janice L. Farlow   +7 more
wiley   +1 more source