Results 121 to 130 of about 11,814,383 (250)

Association between frailty and the cardio-ankle vascular index

open access: yes, 2019
Qi Xue, Ming-zhao Qin, Jing Jia, Jin-ping Liu, Yun Wang Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China Purpose: Frailty and atherosclerotic diseases are prevalent among the older people and usually ...
Liu JP, Qin MZ, Xue Q, Wang Y, Jia J
core  

Acupuncture Alleviates Allergic Rhinitis by Activating the AMPK/PGC‐1α Pathway to Attenuate Mitochondrial Oxidative Stress and Restore Epithelial Barrier Function

open access: yesFlavour and Fragrance Journal, EarlyView.
Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang   +3 more
wiley   +1 more source

A nomogram for predicting oral frailty in older adults: a small-sample cross-sectional study in Anhui Province, China

open access: yesFrontiers in Public Health
BackgroundWith the population aging, oral frailty among older adults has become an increasingly prominent concern. Oral frailty is a condition that is highly prevalent among older adults and has a significant negative impact on their quality of life. The
Huan Liu   +8 more
doaj   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Proportional hazards models with discrete frailty

open access: yes
We extend proportional hazards frailty models for lifetime data to allow a negative bi-nomial, Poisson, Geometric or other discrete distribution of the frailty variable. This might represent, for example, the unknown number of flaws in an item under test.
Crowder, Martin   +2 more
core   +1 more source

Progress in the Role of Mast Cells and Biomolecular Signals in the Mechanism of Postoperative Ileus: From Cellular Activation to Exploration of the Brain–Gut Axis

open access: yesGut Medicine, EarlyView.
ABSTRACT Postoperative ileus (POI) is a frequent complication after surgical procedures, predominantly manifesting as aberrant gastrointestinal motility, which markedly extends the duration of postoperative recovery for patients. The clinical duration of POI is typically modulated by intricate inflammatory cascades, with mast cells assuming a critical ...
Tian‐le Zhang   +4 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

open access: yes, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Secretion of IL-6 and IL-8 from lysophosphatidic acid-stimulated oral squamous cell carcinoma promotes osteoclastogenesis and bone resorption

open access: yes, 2012
Lysophosphatidic acid (LPA) is a bioactive lipid with a growth factor-like activity on a large range of cell types. Several pieces of evidence raise the possibility that LPA may play an important role in bone metastasis.
박광균   +3 more
core  

Oral Frailty: Current Concepts, Assessment, Systemic Implications, and Future Perspectives

open access: yes
Oral frailty has emerged as an important geriatric syndrome characterized by subtle, multifactorial declines in oral function that precede clinically apparent oral dysfunction.
Ken Shinmura   +2 more
core   +1 more source

Defining Biomarkers of Frailty in the Kidney: Implications for Endobiotic and Xenobiotic Metabolism in Mice

open access: yes, 2023
Frailty describes individuals with increased susceptibility to adverse health outcomes. The frailty index (FI) quantifies frailty by measuring deficit accumulation. This project aimed to characterize the molecular signature of frailty in the mouse kidney
Hodgins, Maddison
core  

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