Results 101 to 110 of about 11,814,383 (250)

Goodness-of-fit tests for the frailty distribution in proportional hazards models with shared frailty. [PDF]

open access: yes
Frailty models account for the clustering present in grouped event time data. A proportional hazards model with shared frailties expresses the hazard for each subject. Often a one-parameter gamma distribution is assumed for the frailties. The choice of a
Claeskens, Gerda   +2 more
core  

Investigating the role of frailty in the expression of dementia

open access: yes, 2020
Background: Frailty is related to neuropathological features of Alzheimer’s disease (AD) as well as cognitive decline and dementia. Objectives: 1) determine whether frailty moderates the relationship between neuropathology and dementia status in ...
Wallace, Lindsay M K
core  

Validation of an English version of the Child-OIDP index, an oral health-related quality of life measure for children [PDF]

open access: yes, 2006
Background: To evaluate the psychometric properties of the Child-OIDP for use among children in the UK and report on the prevalence of oral impacts in a sample of schoolchildren in Westminster. Methods: Children aged 10 - 11 years in the final year of
Sheiham, A   +11 more
core   +1 more source

Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

open access: yesBMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu   +10 more
wiley   +1 more source

Physical frailty intensifies the positive association of oral frailty with poor global cognitive function and executive function among older adults especially for females: a cross-sectional study

open access: yesBMC Geriatrics
Background Oral frailty is reported to increase the risk of new onset of mild cognitive impairment. Whereas, the association of oral frailty with cognition among older adults in both physical frail and non-physical frail status has not been sufficiently ...
Yang Fei   +13 more
doaj   +1 more source

Probiotic spore‐based bioresponsive drug delivery for reversing inflammatory bowel disease and its associated anxiety and depression

open access: yesBMEMat, EarlyView.
A probiotic spore‐based drug delivery system (BCS‐Que@ApNPs) provides excellent targeted delivery, bioresponsive drug release, and long‐term retention (over 48 h), making it suitable for oral treatment of inflammatory bowel disease and its associated anxiety and depression.
Qingling Song   +9 more
wiley   +1 more source

Characteristics of drugs with oral frailty patients among community pharmacy visitors: a cross-sectional study

open access: yesBMC Oral Health
Background With the rise in the older population, it has become important to understand the relationship between oral frailty and drug use to consider appropriate medical interventions and drug use for older persons. Objective To clarify the relationship
Ayako Maeda-Minami   +8 more
doaj   +1 more source

Relationship between oral health literacy and oral frailty among older adults in nursing homes: a latent profile analysis

open access: yesFrontiers in Public Health
ObjectivesTo identify different profiles of oral health literacy among older adults in nursing homes and to explore the relationship between these profiles and oral frailty.DesignA cross-sectional study.MethodsA convenience sample of 403 older adults ...
Yang Zhao   +7 more
doaj   +1 more source

Temporal Trends and Prognosis in Rotational Atherectomy: A Comparison of Contemporary and Traditional Eras

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Rotational atherectomy (RA) has undergone considerable technical modernization in recent years. This study evaluated whether RA performed in the contemporary era was associated with superior cardiovascular outcomes compared with the traditional era. Aims To compare the clinical characteristics and cardiovascular outcomes of patients
Ravi Vazirani   +15 more
wiley   +1 more source

Impact of oral frailty on postoperative delirium in older patients undergoing off-pump coronary artery bypass grafting: a prospective observational study

open access: yesBMC Anesthesiology
Background Postoperative delirium (POD) is a frequent and serious complication after cardiac surgery. Although oral frailty has been associated with cognitive decline and systemic inflammation, its role in POD after cardiac surgery remains unclear.
Shizhao Wang   +7 more
doaj   +1 more source

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