Results 181 to 190 of about 11,814,383 (250)

Physical frailty predicts adverse outcomes in hospitalized patients with acute decompensation of cirrhosis

reservedBACKGROUND AND AIM: Patients with end-stage liver disease are at high risk of malnutrition, sarcopenia and frailty. Recent evidence indicates that physical frailty, as assessed by liver frailty index (LFI), is an independent predictor of ...
D'ARCANGELO, FRANCESCA
core  

Survival Outcomes by Frailty and Comorbidities in Veterans Treated With Abiraterone and Enzalutamide for Metastatic Castration‐Resistant Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Androgen receptor pathway inhibitors (ARPIs) such as abiraterone and enzalutamide are common therapies in the management of metastatic castration‐resistant prostate cancer (mCRPC). However, the comparative effectiveness of these oral ARPIs in frail and comorbid patient populations remains uncertain.
Meghana Yellanki, Jennifer La, Danne C. Elbers, Nhan V. Do, Channing J. Paller, Nathanael R. Fillmore, Martin W. Schoen   +6 more
wiley   +1 more source

Association Between Oral Function Limitation and Frailty-Related Functional Impairment in Older Koreans: An Analysis of KNHANES 2024. [PDF]

Healthcare (Basel)
Lee MR.
europepmc   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Preoperative Frailty-Inflammation Phenotypes and Early Functional and Patient-Reported Recovery After Head-and-Neck Oncologic Reconstruction: An Exploratory Prospective Single-Center Cohort Study. [PDF]

J Clin Med
Burtic SR, Capastraru BF, Taskov P, Mihoc T, Levai CM, Kis AM, Fericean RM, Ciortan Sirbu MI, Pop DL, Jianu AM.   +9 more
europepmc   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Association between oral frailty and physical frailty among older adults: a meta-analysis. [PDF]

BMC Oral Health
Li Q, Zhu T, Jiang H, Liu C, Guo H, Du M.   +5 more
europepmc   +1 more source

Magnetothermal‐responsive drug release bone cement based on EGFR‐mutated lung cancer bone metastases

VIEW, EarlyView.
A novel magnetothermal‐responsive bone cement was developed by integrating PMMA/CPC/Osimertinib matrix with Fe3O4@SiO2@Zol nanomaterials. This dual‐drug system achieves controlled release, combining excellent mechanical properties with potent anti‐tumor activity and bone regulation for treating EGFR‐mutated LC‐BoM.
Kandi Xu, Kai Li, Hao Wang, Lishu Zhao, Xinyue Liu, Yujin Liu, Li Ye, Wengang Zhang, Zhimin Chen, Xuyang Chen, Yujie Li, Qianqian Zhang, Wencheng Zhao, Xuebin Zheng, Yu Chen, Yayi He   +15 more
wiley   +1 more source

Frailty in peritoneal dialysis patients: a scoping review. [PDF]

Front Med (Lausanne)
Zheng L, Hu X, Zhong Z, Qiu X, Wang J, Dong L.   +5 more
europepmc   +1 more source