Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
Association Between Oral Frailty and Health Indicators Using Data from the 2023 Korea National Health and Nutrition Examination Survey: A Cross-Sectional Study. [PDF]
Kim SH.
europepmc +1 more source
Frailty and Recovery Following Free Flap Reconstruction in Head and Neck Cancer: A Systematic Review
Abstract Objective To review the impact of frailty on various outcomes in geriatric head and neck cancer (HNC) patients undergoing microvascular free flap reconstruction (MFFR). Data Sources MEDLINE, Embase, and World of Science. Review Methods Following PRISMA guidelines, two independent reviewers performed a systematic review of MEDLINE, Embase, and ...
Anvitha R. Metpally +7 more
wiley +1 more source
Modified 5-Item Frailty Index Is Associated with Postoperative Delirium but Not Survival in Patients Undergoing Surgery for Oral Squamous Cell Carcinoma. [PDF]
Yamagata K +8 more
europepmc +1 more source
Abstract Objective This study investigated the efficacy of a prophylactic, home‐based exercise program administered concomitantly with radiotherapy in patients with head and neck cancer to preserve swallowing function, postural alignment, and cervical range of motion, while assessing lymphedema safety. Study Design Randomized controlled trial.
Burak Erturk +3 more
wiley +1 more source
ABSTRACT Introduction Ambulatory surgery has become the dominant model of surgical care in the United States as surgical procedures increasingly shifted from inpatient to outpatient sites of practice. Similar growth in volumes has been observed in pediatric practice.
Aaron B. Low +4 more
wiley +1 more source
Methodological Cautions Regarding OFI-8 Validation in Healthy Community-Dwelling Older Adults. [PDF]
Qiu C.
europepmc +1 more source
Nutritional status and functions in children with cerebral palsy at different gestational ages
The nutritional status of cerebral palsy was significantly associated with their motor, eating and drinking ability, and their ability of daily living in the 28–32‐week and the ≥37‐week gestational age group, whereas in 33–36‐week group, correlation was only observed between the nutritional status and eating and drinking ability.
Hongmei Tang +14 more
wiley +1 more source
Abstract Background Hypovitaminosis D is associated with adverse health outcomes, including increased mortality in patients with cancer. Although vitamin D insufficiency (23%–72%) and deficiency (20%–71%) are common among patients admitted to inpatient rehabilitation, their prevalence and predictors in cancer‐specific inpatient rehabilitation ...
Jegy M. Tennison +7 more
wiley +1 more source
Unveiling the link between oral microbial α-diversity, advanced cardiovascular-kidney-metabolic syndrome, and mortality. [PDF]
Zhang Z, Ji H, Xu Y, Song Y, Chen J.
europepmc +1 more source

