Results 91 to 100 of about 7,425,496 (297)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Global trends in the application of digital technology in jaw reconstruction: A bibliometric and visualization analysis

open access: yesDigital Health
Background The application of digital technology in jaw reconstruction is clinically significant as it enhances surgical precision and patient outcomes.
Xu Xiang   +4 more
doaj   +1 more source

Oral manifestation of paraneoplastic pemphigus [PDF]

open access: yes, 2019
Paraneoplastic pemphigus (PNP) is a rare and often fatal autoimmune blistering disease accompanied by both benign and malignant neoplasms. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by PNP patients.
박연정   +3 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Improvements in oral functions of elderly after simple oral exercise.

open access: yesClinical interventions in aging, 2019
Purpose: Conventional oral exercises in previous studies are considered impractical for continuous use in the elderly because of the extended duration needed for effective outcomes. Therefore, in the present study, a simple oral exercise (SOE) was developed to reduce performance time, focusing on improvements in mastication, salivation, and swallowing ...
Kim,Hyo-Jung   +5 more
openaire   +3 more sources

The Association of Oral Function with Oral Health-Related Quality of Life in University Students: A Cross-Sectional Pilot Study

open access: yes, 2020
The aim of this cross-sectional study was to investigate the association between oral function and oral health-related quality of life (OHRQoL) in healthy university students.
Shinsuke Mizutani   +7 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Morphological Characterizations and Mineralized Repair of Natural Tooth Cracks Via Self-Assembling Peptide Hydrogels

open access: yesInternational Dental Journal
Introduction and aims: This study aimed to investigate the distribution and morphology of cracks in natural cracked teeth and evaluate the potential of self-assembling peptide hydrogels (L-gel: Nap-FFG-DHTKE and D-gel: Nap-DFDFG-DHTKE) as biomimetic ...
Zhenying Zheng   +8 more
doaj   +1 more source

Oral health-related quality of life after dental treatment in patients with intellectual disability

open access: yes, 2020
Background: The influence of dental treatment on oral health-related quality of life (OHRQOL) has rarely been evaluated in patients with intellectual disability (ID) through validated questionnaires.
Toledano Valero, Pilar   +7 more
core   +1 more source

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