Results 81 to 90 of about 7,425,496 (297)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Oral Contraception and Liver-function Tests [PDF]

BMJ, 1965
The effects of oral contraceptives (OCs) on liver function were stud ied in 243 women over a period of 6-18 months. The subjects received a combined regimen of 2 mg norethindrone and .075 mg mestranol. Liver function tests revealed abnormally elevated levels of bromosulphthalein retention in 42% of the cases of thymol turbidity in 11% of SGPT in 7 ...
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Regional differences in perceived oral dryness as determined with a newly developed questionnaire, the Regional Oral Dryness Inventory

, 2020
OBJECTIVES: Several questionnaires, such as the internationally validated and frequently used Xerostomia Inventory (XI), have been developed to quantify the subjective feeling of a dry mouth.
Mashhour, E, Brand, H S, Assy, Z.; id_orcid, Bikker, F.J., Bikker, F.J.; id_orcid, Jager, D H J, Bikker, F J, Jager, D.H.J., Brand, H.S.; id_orcid, Assy, Z., Mashhour, E., Assy, Zainab, Brand, H.S.   +12 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Effect of smoking on MUC1 expression in oral epithelial dysplasia, oral cancer, and irradiated oral epithelium

, 2022
Objectives: The aim of this study was to assess the MUC1 expression in the oral epithelium of normal, oral epithelial dysplasia (OED), oral squamous cell carcinoma (OSCC), and irradiated oral epithelium (IROE) and its association with smoking habits in ...
Schulten, Engelbert A. J. M., Mikkonen, Jopi J.W., Dekker, Hannah, Bhardwaj, Tulika, Kullaa, Arja M., Kashyap, Bina, Bloemena, Elisabeth, Mikkonen, Jopi J. W., Schulten, Engelbert A.J.M.   +8 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Case-based virtual reality simulation for penetrating facial wound suture skill training in medical students: design and pilot study

BMC Medical Education
Background Virtual Reality (VR) technology has become an essential preclinical training tool in the field of oral and maxillofacial surgery education.
Yan Zhang, Shuai Nie, Yanmei Dai, Yingbin Yan   +3 more
doaj   +1 more source

Prevalence of Oral Pain and Barriers to use of Emergency Oral Care Facilities Among Adult Tanzanians. [PDF]

, 2008
Oral pain has been the major cause of the attendances in the dental clinics in Tanzania. Some patients postpone seeing the dentist for as long as two to five days.
Kikwilu Emil, Febronia Kokulengya Kahabuka, Masalu, Joyce Rose, Kikwilu, Emil Namakuka, Senkoro, Ahadieli Raphael, Kahabuka Febronia, Masalu, J.R., Joyce Rose Masalu, Emil Namakuka Kikwilu, Ahadieli Raphael Senkoro, Kahabuka, Febronia Kokulengya, Senkoro Ahadieli, Masalu Joyce, Kikwilu, E.N., Kahabuka, F.K., Senkoro, A.R.   +15 more
core   +2 more sources