Multi‐omics–driven precision medicine
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
Functional Advantage of Central Pancreatectomy Over Distal Pancreatectomy for Benign or Low-Grade Malignant Tumors: A Comparative Analysis Based on 75-g Oral Glucose Tolerance Test. [PDF]
Lee D +9 more
europepmc +1 more source
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu +3 more
wiley +1 more source
Hypoglycaemia During Oral Glucose Tolerance Test in Pregnancy and Feto-Maternal Outcomes: A Systematic Review and Meta-Analysis. [PDF]
Dutta D +5 more
europepmc +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
The recurrence risk of gestational diabetes according to the number of abnormal values in the oral glucose tolerance test. [PDF]
Pukkila J +10 more
europepmc +1 more source
Metrnl: A Novel Therapeutic Target in Atherosclerosis
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley +1 more source
Diagnostic performance of 1-hour plasma glucose and glucose curve shape during oral glucose tolerance test: a cross-sectional study in a Brazilian cohort. [PDF]
Castro JPFC +5 more
europepmc +1 more source

