Results 61 to 70 of about 22,582,335 (276)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The influence of North Korean defectors’ oral health service experience on oral health behavior [PDF]

, 2022
Objectives: The study aims to investigate the influence of oral health service experience on oral health behavior of North Korean defectors and contribute to the development and implementation of oral health education among this population.
김시우, 권재성, 이재훈
core   +1 more source

Xerostomia in Dialysis Patients—Oral Care to Reduce Hyposalivation, Dental Biofilms and Gingivitis in Patients with Terminal Renal Insufficiency: A Randomized Clinical Study

Kidney and Dialysis, 2023
Objectives: Dialysis patients suffer from xerostomia based on hyposalivation even in stimulated saliva testing. Therefore, the aim of this study was (i) to evaluate an optimized oral hygiene system with an oral care gel reducing oral dryness, supporting ...
Leonie C. Egbring, Tomas Lang, Burkhard Kreft, Karl W. Weich, Peter Gaengler   +4 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The Croatian Version of the Oral Health Impact Profile Questionnaire

Collegium antropologicum, 2009
Purpose of this study was to develop a Croatian version of the Oral Health Impact Profile questionnaire (OHIP--CRO49), following the accepted cross-cultural adaptation technique guidelines. The original version was translated by using a forward-backward translation method. The psychometric properties of the OHIP-CRO49 were tested. To test the construct
Petričević, Nikola, Čelebić, Asja, Papić, Milan, Rener-Sitar, Ksenija   +3 more
openaire   +5 more sources

Assessment of the relationship between periodontal clinical parameters and oral health-related quality of life

Van Tıp Dergisi, 2018
INTRODUCTION: Oral health-related quality of life (OHRQoL) to refers to how social, psychological, functional factors and problems affect the well-being of people in the oral region.
Hacer Şahin Aydınyurt, Dicle Altındal
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The prevalence and impact of teeth wear on oral health related quality of life among rural adult population of Sullia taluk, D.K

Journal of Indian Association of Public Health Dentistry, 2018
Introduction: Teeth wear (TW) an otherwise physiological process if present above acceptable level might cause a debilitating effect on the quality of life (QoL).
Jaseela Praveena, Hemant Battur, Nusrath Fareed, Sanjeev Khanagar   +3 more
doaj   +1 more source

Developing a new self-reported scale of oral health outcomes for 5-year-old children (SOHO-5) [PDF]

, 2012
Background: Information on the impact of oral health on quality of life of children younger than 8 years is mostly based on parental reports, as methodological and conceptual challenges have hindered the development of relevant validated self-reported ...
Macpherson, L.M.D., Lorna M D Macpherson, Yvonne I Blair, Huda Yusuf, Wright, W., Georgios Tsakos, Blair, Y.I., Watt, R.G., Tsakos, G., Yusaf, H., William Wright, Richard G Watt, Yusuf Huda, Macpherson Lorna M D, Wright William, Watt Richard G, Blair Yvonne I, Tsakos Georgios   +17 more
core   +1 more source