Results 71 to 80 of about 22,582,335 (276)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Oral health impact profile(OHIP) according to the oral health behavior of foreign workers

Journal of Korean society of Dental Hygiene, 2015
Objectives: The objective of this study is to investigate oral health behavior, PHP index and OHIP, awareness, attitude and behavior toward oral health in the foreign factory workers. Thsi study will provide the basic data for the improvement of the foreigners’ quality of life. Methods: A self-reported questionnaire was completed by 126 Sri Lankans and
Sung-Uk Yoon, In-Suk Nam
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effectiveness, cost-effectiveness and cost-benefit of a single annual professional intervention for the prevention of childhood dental caries in a remote rural Indigenous community [PDF]

, 2015
Background The aim of the study is to reduce the high prevalence of tooth decay in children in a remote, rural Indigenous community in Australia, by application of a single annual dental preventive intervention.
Surani Fernando, Ratilal Lalloo, Yvonne Cadet-James, Tut, Ohnmar, Kularatna, Sanjeewa, Scuffham, P.A., Scuffham, Paul A, Jamieson, Lisa M., Kularatna, S., Paul A. Scuffham, Fernando, Surani, Valda Wallace, Kroon, J., Tut, O., Boase, R., Lisa M. Jamieson, Robyn Boase, Newell W. Johnson, Wallace, V., Jeroen Kroon, Lalloo, Ratilal, Jamieson, L.M., Boase, Robyn, Johnson, Newell W., Ohnmar Tut, Cadet-James, Yvonne, Kroon, Jeroen, Sanjeewa Kularatna, Scuffham, Paul A., Lalloo, R., Johnson, N.W., Johnson, Newell W, Jamieson, Lisa M, Wallace, Valda, Fernando, S., Cadet-James, Y.   +35 more
core   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The impact of osteogenesis imperfecta severity on oral health-related quality of life in Spain: a cross-sectional study

Orphanet Journal of Rare Diseases
Background Osteogenesis imperfecta (OI) affects dental and craniofacial development; therefore, it can influence oral health-related quality of life (OHRQoL).
Amira Ahmed Elfituri, Manuel Joaquín De Nova, Mohammadamin Najirad   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Evaluating Oral Health Status, Oral Lesions Prevalence, and Oral Health Impact Profile-14 among Tobacco Industry Workers

Indian Journal of Dental Sciences
Background: Maintaining optimal oral health is critical for general well-being, particularly in occupational settings where unique hazards may impact oral health. The purpose of the present study is to comprehensively examine the oral health implications
Grandhi Srujananjali, K. Ramya, Roja Lakshmi Karri, Krishna Sahi Bonthagarla, Akkineni Bhavya Sree, Yannam Mounika   +5 more
doaj   +1 more source

Ultra‐short version of the oral health impact profile in elderly Chileans

Geriatrics & Gerontology International, 2016
AimThe aim of the present study was to develop and validate an ultra‐short Spanish version of the Oral Health Impact Profile (OHIP) in an elderly Chilean population.MethodsThe OHIP‐49Sp was applied to 490 older adults, and the seven questions with the higher impact on oral health‐related quality of life were selected through linear regression.
Soraya León, Gloria Correa‐Beltrán, Renato J De Marchi, Rodrigo A Giacaman   +3 more
openaire   +4 more sources