Results 241 to 250 of about 185,181 (311)

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Safety and Efficacy of Early Aspirin Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT): Rationale and Design of a Multicenter, Randomized, Placebo-Controlled Clinical Trial. [PDF]

J Am Heart Assoc
Wang J, Li S, Liu L, Ma Q, Li C, Wu C, Wu L, Song H, Ji X, Zhao W.   +9 more
europepmc   +1 more source

Hepatic transplantation [PDF]

, 1964
Starzl, TE
core  

A Review of Virtual Twins in Physiologically‐Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacology &Therapeutics, EarlyView.
The novel application of Virtual Twins (VT) in PBPK (VT‐PBPK) presents the opportunity to advance precision dosing and accelerate the shift from one‐size‐fits‐all to targeted, individualized treatments. This review aims to: (1) critically evaluate existing research on the use of VTs in PBPK, (2) develop a conceptual definition of VT‐PBPK, (3) describe ...
Emily Mannix, Sam Mostafa, Amin Rostami‐Hodjegan, Thomas M. Polasek, Carl M. J. Kirkpatrick   +4 more
wiley   +1 more source

Effect of intranasal breast milk administration on cerebral oxygenation, vital signs, and transition time to full oral feeding in preterm infants: a randomized controlled study. [PDF]

Eur J Pediatr
Yücel A, Küçükoğlu S, Konak M.
europepmc   +1 more source

Appendiceal Dieulafoy's Lesion: A Rare Cause of Lower Gastrointestinal Bleeding. [PDF]

Surg Case Rep
Hoshino N, Yamamoto J, Takei S, Shimizu Y, Tanaka Y, Yabuno T, Hayashi H, Mochizuki Y.   +7 more
europepmc   +1 more source

Clinical Significance of an Incidentally Detected Lateral Lingual Foramen on Cone-Beam Computed Tomography (CBCT): A Case Report and Review of Pertinent Literature. [PDF]

Cureus
Ramalingam S, Alamri AA, Almujali AA, Alqarni A, Alalwan AG, Alrefaei FM.   +5 more
europepmc   +1 more source

The clinical trial of FK 506 as primary and rescue immunosuppression in pediatric cardiac transplantation [PDF]

, 1991
Armitage, JM, Cipriani, L, Del Nido, P, Fricker, FJ, Starzl, TE   +4 more
core  

Ischemic stroke complicated by intracerebral hemorrhage in patients with hypereosinophilic syndrome: a case series. [PDF]

Ther Adv Neurol Disord
Hidaka M, Mezuki S, Yokoi M, Osaki M, Akiyama T, Yamaguchi S, Sayama T, Ago T, Arakawa S.   +8 more
europepmc   +1 more source

Real‐World Comparison of Vascular Access Closure Strategies in TAVI

Catheterization and Cardiovascular Interventions, EarlyView.
Saif Zako, Kathrin Klein, Karin Alde, Christian Jung, Verena Veulemanns, Maximilian Scherner, Artur Lichtenberg, Malte Kelm, Tobias Zeus, Amin Polzin   +9 more
wiley   +1 more source