Results 41 to 50 of about 6,561,266 (328)
Applied Sciences, 2020 The aim of the study is to observe retrospectively the correlation between Oral Squamous Cell Carcinoma (OSCC) and risk factors; including tobacco, alcohol and Family History of Cancer (FHC). A total of 478 patients were included retrospectively from the
G. Tenore +21 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Marosvásárhelyi színész(ek) a Ceausescu korszakban. Életút interjúk pszichológiai megközelítésben
Symbolon, 2021 Actors from Târgu-Mureș in the Ceaușescu Regime. Life-course Interviews From a Psychological Point of View Our research is based on life-course interviews with Romanian and Hungarian actors.
Kinga Bakk-Miklósi
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The evolutionary history of the human oral microbiota and its implications for modern health.
Periodontology, 2020 Numerous biological and cultural factors influence the microbial communities (microbiota) that inhabit the human mouth, including diet, environment, hygiene, physiology, health status, genetics, and lifestyle.
L. Weyrich
semanticscholar +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
搶救過去的記憶 : 口述歷史應用在圖書館之探析 Save the Memory：The study of oral history in the library [PDF]
Jiàoyù zīliào yǔ túshūguǎn xué, 2003 口述歷史是透過人們的回憶所建構起來的歷史。近年來口述歷史的應用更為昔遍，不僅許多學科領域及民間歷史團體紛紛運用口述歷史方法豐富自身歷史的維度，更大的意義在於口述歷史為長期被忽略的階層及社群提供發言的位置。本文即以口述歷史建構史料的角度出發，探討圖書館史與口述歷史的關係，分析美國與台灣的圖書館界從事口述歷史的情況，目的在喚起圖書館界同仁搶救圖書館歷史的危機意識，免於日後這些活歷史渺茫難覓的遺憾。Oral history is a historical approach that is based on ...
Sheue-fang Song, Shih-ying Shiu
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