Results 51 to 60 of about 6,561,266 (328)

What Makes Oral History Different

open access: yesWrocławski Rocznik Historii Mówionej, 2018
A text from the age of great debates on the scientific status of research based on material considered by many historians to be of questionable value. In his paper, Alessandro Portelli deals with the doubts and accusations made not only then, but also ...
Alessandro Portelli
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The Development of Oral History in the United States: the evolution toward interdisciplinary

open access: yesTempo e Argumento, 2018
This article discusses the development of oral history in the United States and how this has led the field to becoming interdisciplinary in interesting and useful ways.
David king Dunaway
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Natural History of Nonhuman Primates After Oral Exposure to Ebola Virus Variant Makona [PDF]

open access: green, 2023
Abhishek N. Prasad   +10 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Forced Labor in Nazi Germany: Online Archive of Interviews and Related Educational Online Platform

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2019
Introduction.The article deals with the problem of forced labor in Nazi Germany during the Second World War. Despite the existence of profound scientific publications devoted to this problem in Russia and abroad, it still needs to be developed.
Doris Tausendfreund   +2 more
doaj   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Voicing New Identities. Two Case-Studies of Oral History and Displacement in WW2 and its Aftermath [PDF]

open access: yesClose Encounters in War Journal, 2019
The current refugee crisis is unprecedented, and it prompts many questions on how to tackle the emergency and on the mechanisms of international humanitarian aid.
Simona Tobia
doaj  

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