Results 81 to 90 of about 10,211 (187)
A Proposed Clinical Diagnostic Framework for Short Telomere Syndrome
We propose a phenotype‐based diagnostic framework for short telomere syndrome that integrates age‐adjusted telomere length, phenotypic manifestations, and genetic findings, where available. The framework is intended to guide clinical evaluation, longitudinal surveillance, and individualized management while acknowledging limitations in current telomere
Andrew Courtwright +8 more
wiley +1 more source
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer +4 more
wiley +1 more source
ABSTRACT Oral cancer (OC) remains a therapeutic challenge due to limited validated targets. Cis‐pQTLs from the deCODE cohort (n = 35,559) were harmonized with OC‐GWAS (3547 cases and 691,466 controls) meta‐data through a two‐sample Mendelian randomization (MR) framework.
Meishan Huang +9 more
wiley +1 more source
ABSTRACT Objective To estimate the risk for oral squamous cell carcinoma (OSCC) among patients with oral lichen planus (OLP) or lichenoid lesions (OLL) and the possible risk factors. Material and Methods Two hundred thirty‐nine OLP and 84 OLL patients diagnosed between years 1982 and 2017 were followed up to December 2023, diagnosis of an OSCC, or ...
Mari Vehviläinen +3 more
wiley +1 more source
Hemidesmosomal Proteins in Oral Cancer Progression: An Immunohistochemical Study of Human and Mouse
ABSTRACT Background Hemidesmosomal subunits have gained attention for their potential role in the progression of oral squamous cell carcinoma (OSCC). However, formal analysis of quantitative expression patterns correlating with OSCC disease pathogenesis remains limited.
Nikhil Mongia +10 more
wiley +1 more source
Background: Human papillomavirus (HPV) and p53 alterations are speculated to play a role in carcinogenesis. This study was carried out to find out the association of HPV and p53 with precancerous lesions of the oral cavity such as leukoplakia: The ...
Seema Sikka, Pranav Sikka
doaj
ABSTRACT Background Oral potentially malignant disorders (OPMDs) represent a diverse group of mucosal disorders with varying risks of progression to oral cancer. Objective This updated systematic review (SR) and meta‐analysis (MA) estimated the global prevalence of histopathologically confirmed OPMDs, excluding oral lichen planus and lichenoid lesions.
Nicole Lonni +6 more
wiley +1 more source
ObjectiveThe present study aims to employ and compare the artificial intelligence (AI) convolutional neural networks (CNN) Xception and MobileNet-v2 for the diagnosis of Oral leukoplakia (OL) and to differentiate its clinical types from other white ...
Elakya Ramesh +3 more
doaj +1 more source
Models of Oral Epithelial Dysplasia: A Systematic Review and Temporal Analysis
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck, associated with substantial morbidity and mortality worldwide. Oral epithelial dysplasia (OED) can precede OSCC, offering a critical window for preventive and therapeutic intervention.
Zilefac Brian Ngokwe +4 more
wiley +1 more source

