Results 121 to 130 of about 213,921 (300)

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

Animal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat, Chatsuree Suksamai, Dhammika Leshan Wannigama, Kent Doi, Wiwat Chancharoenthana, Asada Leelahavanichkul   +5 more
wiley   +1 more source

Effect of the Oral Probiotics on Salivary Alpha-amylase, Buffering Capacity, pH, and Plaque Level among Dental Students – A Pilot Randomized Controlled Trial

Journal of Indian Association of Public Health Dentistry
Background: Saliva has been used as a potential diagnostic tool due to its ease, noninvasive accessibility, along with its numerous biomarkers. The use of salivary alpha amylase (SAA) as a biomarker for various diseases including carious lesion is a ...
S. Savitha Priyadarsini, Kamlesh Manohar Palandurkar, P. G. Naveen Kumar, Mahesh R. Khairnar, Zainab Akram, Ridhi Ghodela, Sachin Kumar Jadhav, Neha Shukla   +7 more
doaj   +1 more source

Interferometry meets the third and fourth dimensions in galaxies

, 2014
Radio astronomy began with one array (Jansky's) and one paraboloid of revolution (Reber's) as collecting areas and has now reached the point where a large number of facilities are arrays of paraboloids, each of which would have looked enormous to Reber ...
Trimble, Virginia
core   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

Heterogenous Model of Temozolomide Resistance in Glioblastoma Reveals Phenotypic Shifts in Drug Response and Migratory Potential

Advanced NanoBiomed Research, EarlyView.
Glioblastoma mortality is driven by cell invasion and therapeutic resistance. We report a cancer engineering approach to evaluate the behavior of heterogeneous cohorts of temozolomide resistant and responsive GBM cells. We show the effect of physiologically‐relevant metronomic dosing on ensemble drug response and invasion.
Victoria A. Kriuchkovskaia, Ela K. Eames, Sydney A. McKee, Paul J. Hergenrother, Rebecca B. Riggins, Brendan A. C. Harley   +5 more
wiley   +1 more source

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

The Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum, Michael J. Blumer, Mason N. Dean, Laura J. Ekstrom   +3 more
wiley   +1 more source

Functional anatomy, jaw mechanisms, and feeding behavior of Dunkleosteus terrelli (Placodermi, Arthrodira)

The Anatomical Record, EarlyView.
A new musculoskeletal reconstruction and revision of the cranio‐mandibular anatomy of the Devonian arthrodire placoderm Dunkleosteus terrelli from a comparative and functional anatomical perspective. Dunkleosteus is a specialized arthrodire with many specializations for feeding on large vertebrates, and many of its features are part of broader ...
Russell K. Engelman, Robert K. Carr, Kate Trinajstic, Zerina Johanson, Oleg A. Lebedev   +4 more
wiley   +1 more source

Delphine Red Shirt: George Sword's Warrior Narratives: Compositional Processes in Lakota Oral Tradition [PDF]

, 2018
George Sword an Oglala Lakota (1846–1914) learned to write in order to transcribe and preserve his people’s oral narratives. In her book Delphine Red Shirt, also Oglala Lakota and a native speaker, examines the compositional processes of George Sword ...
Phillips, Rachel Sherman
core  

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

The Relation between Heat strain and hydration status among

Muhandisī-i bihdāsht-i ḥirfah/ī, 2016
Introduction: during the physical activity in hot environments, sweating with evaporation, the important physiological response of the body  increases which can be lead to dehydration .
Somayeh Bolghanabadi, Mehdi Pour, Ali akbar Mohamadi, Mahdi Tizro   +3 more
doaj