Results 181 to 190 of about 1,659,411 (286)

Drugstore or discount? A study on fluoride, pH and acidity of commercial mouthwashes in Riyadh, Saudi Arabia. [PDF]

Front Oral Health
Alshenaiber R.
europepmc   +1 more source

Trends and Future Directions in Organic Chemistry for Drug Discovery

Chemistry – A European Journal, EarlyView.
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley   +1 more source

Mandibular Advancement for Obstructive Sleep Apnea: Efficacy and the Trade-off of Expiratory Velopharyngeal Obstruction During Sleep Endoscopy - An Exploratory Observational Study. [PDF]

Nat Sci Sleep
Lo SC, Hsu YS, Lin YH, Kuo YE, Chen TY, Yang CCH.   +5 more
europepmc   +1 more source

Unraveling the Multimodal Oncogenic Network of KITENIN: From Metabolic Reprogramming and Microenvironment Remodeling to Targeted Interventions

Cancer Nexus, EarlyView.
ABSTRACT KAI1 C‐terminal interacting tetraspanin (KITENIN) is an emerging oncogenic regulator associated with tumorigenesis, metastasis, therapeutic resistance, and poor clinical outcomes. Mechanistically, KITENIN promotes tumor cell proliferation, migration, invasion, and epithelial–mesenchymal transition (EMT) by activating oncogenic pathways ...
Niaz Mahmood Tanoy, Zarin Tasnim, Md Shiblee Sadik Sabuj, Tanvir Ahmed, Md Abdul Momin, Md Sadekuzzaman, Sumaia Islam Mow, Md Aktaruzzaman, Md Rashedunnabi Akanda   +8 more
wiley   +1 more source

Meter Standard

A steel line meter standard marked NBS No.

core  

The Multiple Criteria Qualitative Value‐Based Pricing Framework “MARIE” for Novel Cell and Gene Therapy

Clinical Pharmacology &Therapeutics, EarlyView.
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley   +1 more source

Peak Flow Meter and Spacer Use in Adolescents with Asthma: More than Just Ownership. [PDF]

Children (Basel)
Rhee H, Katchamat N.
europepmc   +1 more source

Time‐Dependent Bias and Prognostic Confounding in Exposure–Response Analysis of Targeted Therapies: Lessons from Sunitinib in Metastatic Renal Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure–response (E–R) analyses of sunitinib in metastatic renal cell carcinoma (mRCC) have supported concentration‐guided dose escalation. However, such analyses may be biased when exposure metrics incorporate post‐baseline dose modifications, time‐varying apparent clearance, or baseline factors that influence both pharmacokinetics and clinical ...
Han Liu, Lena E. Friberg
wiley   +1 more source

A battery-free wireless intelligent aligner for spatially resolved, closed-loop theranostics of chronic oral diseases. [PDF]

Sci Adv
Zhang W, Hu W, Li C, Wang K, Shi F, Liu F, Wang L, Xu L.   +7 more
europepmc   +1 more source

Exposure‐Response Analyses of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Advanced Non‐small Cell Lung Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure‐response analyses supported a favorable benefit‐risk profile of Dato‐DXd at 6 mg/kg Q3W in patients with advanced nonsquamous NSCLC. Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell‐surface antigen‐2 (TROP2)‐directed antibody‐drug conjugate (ADC) that has demonstrated clinical activity in patients with NSCLC who have received prior ...
Ying Hong, Anna M. Mc Laughlin, Yuzhuo Pan, Sofia Friberg Hietala, Sophie Peigné, Michael Chargualaf, Zoey Tang, Diansong Zhou, Naoyuki Tajima, Malaz Abutarif, Tushar Garimella   +10 more
wiley   +1 more source