Results 191 to 200 of about 1,659,411 (286)

Machine learning-based modeling and analysis of solubility behavior in supercritical CO₂ systems under different operating conditions. [PDF]

Front Med (Lausanne)
Khoshaim AB.
europepmc   +1 more source

From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs

Clinical Pharmacology &Therapeutics, EarlyView.
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley   +1 more source

Salivary pH within multifactorial caries risk assessment in children: observational clinical evidence using the Cariogram platform. [PDF]

Front Oral Health
Barbulescu ED, Cristache CM, Vacarel EV, Nimigean VR.   +3 more
europepmc   +1 more source

Evaluating Vaginal Microbiome Effects on Antiretroviral Exposure in the Female Genital Tract Using Pharmacometric and Machine Learning Approaches

Clinical Pharmacology &Therapeutics, EarlyView.
Antiretroviral pre‐exposure prophylaxis (PrEP) is less effective in women than expected, partly because drug exposure within the female genital tract is variable and may be influenced by the vaginal microbiome. We developed an integrated pharmacometrics and machine learning framework to evaluate associations between vaginal microbiome composition and ...
Diqin Yan, Lindsey B. Collins, Christopher Staley, Flavia Kiweewa Matovu, Pamala Jacobson, Melanie Nicol, Shen Cheng   +6 more
wiley   +1 more source

The effects of caffeinated chewing gum on sprint swimming performance and upper-body strength: a randomized crossover study. [PDF]

BMC Nutr
Serpa MC, de Souza Dos Santos J, de Oliveira MF, Borszcz FK, Turnes T, de Lucas RD, Guglielmo LGA.   +6 more
europepmc   +1 more source

Driving International Revenue Growth Through Social Sustainability: Insights for Corporate Social Responsibility

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Firms' international revenues help diversify revenue sources and reduce reliance on home markets, yet remain hard to grow given complex regulations, cultural differences and fierce competition. Grounded in the resource‐based view, we argue that social sustainability is a valuable, rare, inimitable and non‐substitutable resource that promotes ...
Ashutosh Singh, Salwa Saleh Almasabi, Diana Korayim, Judit Petra Koltai   +3 more
wiley   +1 more source

Fasting gut hormone levels following long-term recovery from Anorexia Nervosa: A cross-sectional study. [PDF]

J Eat Disord
Kolb T, Tam FI, Förster Ribet C, Ohme M, Schlolaut LC, King JA, Roessner V, Dickson SL, Pariante CM, Borsini A, Perakakis N, Ehrlich S.   +11 more
europepmc   +1 more source

Beyond BMI: Unsupervised Machine Learning Clustering of Bioelectrical Impedance Phenotypes Is Associated With Weight‐Recovery Trajectories in Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To identify data‐driven body composition phenotypes in patients with moderate‐to‐extreme anorexia nervosa (AN) using machine learning (ML) clustering of bioelectrical impedance analysis (BIA) parameters, and to test whether these phenotypes have specific psychopathological and childhood trauma profiles while correlating with early ...
Emanuele Cassioli, Gaia Maiolini, Eleonora D'Areglia, Livio Tarchi, Eleonora Rossi, Veronica Ceccarelli, Cristiano Dani, Luca Zompa, Chiara Ranieri, Enrico Lodovici, Anita Nannoni, Valdo Ricca, Giovanni Castellini   +12 more
wiley   +1 more source

Comparative evaluation of human breast milk, cow milk, infant formula and almond milk on childhood cariogenicity: An <i>in vivo</i> study. [PDF]

Bioinformation
Debnath A, Jawa D, Jaidka S, Chaudhary N, Selseya R, Bhattacharya S.   +5 more
europepmc   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source