Results 321 to 330 of about 2,361,676 (390)

Anti‐inflammatory and Gastroprotective Effects of the Chamaerops humilis L. (DOUM) Fruit Aqueous Extract in Experimental Models of Edema and Gastric Ulcer

Chemistry &Biodiversity, EarlyView.
ABSTRACT Chronic inflammation can lead to various diseases, including gastric ulcers, highlighting the need for effective therapeutic strategies. The traditional use of Chamaerops humilis in Moroccan folk medicine for treating gastrointestinal disorders underscores its potential as a valuable natural remedy.
Yasmina Jaouhari, Hamid Kabdy, Ouijdane El hatimy, Hajar Azraida, Baslam Abdelmounaim, Abdelfattah Aitbaba, Laadraoui Jawad, Yassine Chait, Rachida Aboufatima, Soad Moubtakir, Loubna El Yazouli, Stefania Garzoli, Abderrahman Chait   +12 more
wiley   +1 more source

Editorial: Oral mucosa and disorders: from drug discovery to development and translation. [PDF]

Front Pharmacol
Ghate V, Alqahtani MS, Shah H, Veena KM.
europepmc   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Development of a Multilayer Film Including the Soluble Eggshell Membrane Fraction for the Treatment of Oral Mucosa Lesions. [PDF]

Pharmaceutics
Neduri K, Ailuno G, Zuccari G, Bassi AM, Vernazza S, Schito AM, Caviglioli G, Baldassari S.   +7 more
europepmc   +1 more source

SIRT7‐Mediated MVP Desuccinylation Facilitates Tongue Squamous Cell Carcinoma Progression by Activating JAK2/STAT3 Pathway

Cell Biology International, EarlyView.
ABSTRACT Major vault protein (MVP) plays a contributing role in multifarious cancers, and then its role in Tongue squamous cell carcinoma (TSCC) is uncomprehending. This study aimed to investigate the regulatory effect of MVP on malignant behavior of TSCC cells and its mechanism. We first pointed out the abnormal upregulation of MVP in tumor tissues by
Zhuo Zhang, Tingting Guo, Xiangyu Zhao
wiley   +1 more source

Pilot Evaluation of Silicone Surrogates for Oral Mucosa Simulation in Craniofacial Surgical Training. [PDF]

Biomimetics (Basel)
Cin MD, Koka K, Darragh J, Nourmohammadi Z, Hamdan U, Zopf DA.   +5 more
europepmc   +1 more source

Manganese Neurotoxicity and Familial Disorders of Manganese Transport

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley   +1 more source

Exploring the Regulators of Keratinization: Role of BMP-2 in Oral Mucosa. [PDF]

Cells
Mu X, Ono M, Nguyen HTT, Wang Z, Zhao K, Komori T, Yonezawa T, Kuboki T, Oohashi T.   +8 more
europepmc   +1 more source

Advancing Predictions of Oral Drug Absorption, CYP3A4 Induction, and Transporter‐Mediated Interactions Using a Human Primary Intestinal 3D Model (EpiIntestinal™)

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate prediction of oral drug absorption in humans is essential for early drug development; however, physiologically relevant human models are lacking. This study aims to comprehensively assess the EpiIntestinal™, a human primary intestinal 3D model, for its ability to predict oral absorption (Fa), intestinal availability (Fg), CYP3A4 induction, and
Paresh P. Chothe, Andrea Whitcher‐Johnstone, Aniruddha Karve, Diane Ramsden, Niresh Hariparsad   +4 more
wiley   +1 more source

Single-cell RNA-seq reveals a resolving immune phenotype in the oral mucosa. [PDF]

iScience
Cantalupo P, Diacou A, Park S, Soman V, Chen J, Glenn D, Chandran U, Clark D.   +7 more
europepmc   +1 more source